Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
respiratory sensitisation: in vivo
Type of information:
other: case reports form employment protection
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: case reports form employment protection

Data source

Reference
Reference Type:
other: medical case reports
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Knowlaege for employment protection,, case reports
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
sannous oxalate
IUPAC Name:
sannous oxalate
Details on test material:
no data

Test animals

Species:
other: Homo sapiens
Strain:
not specified
Sex:
male/female

Test system

Route of induction exposure:
inhalation
Route of challenge exposure:
inhalation
Vehicle:
other: dust in air
Positive control substance(s):
none
Negative control substance(s):
none

Results and discussion

Results:
affter a first exposure to stannous oxalate (e.g. opening a sample container in the room) most of the workers react at once with intensive sneezing, epistaxis turgor of the eyes and nose

Applicant's summary and conclusion

Interpretation of results:
Category 1 (respiratory sensitising) based on GHS criteria
Conclusions:
stannous oxalate causes Respiratory sensitisation

Categories Display