3-Oxabicyclo[3.1.0]hexan-2-one, 4-hydroxy-6,6-dimethyl-, (1R,4R,5S)-

Guidance on Safe Use

First-aid measures

If inhaled and experiencing any discomfort, remove from exposure. Get medical attention immediately if symptoms develop.

If swallowed and the exposed person is conscious, let him/her rinse mouth and give several glasses of water or milk if available, but do not induce vomiting. If vomiting occurs, give several glasses of fluid again. Never give anything by mouth to an unconscious person. Make the exposed person lie down and keep him/her steady. Get medical attention immediately.

If in eyes, immediately rinse with large amounts of water or eyewash solution, occasionally opening eyelids, until no evidence of chemical remains. Remove contact lenses after a few minutes and rinse again. Get medical attention immediately.

If on skin, immediately flush skin with plenty of water while removing contaminated clothing and shoes. See physician if needed.

Irritation should be treated as usual against effects of acids or acid fumes.

For ingestion, consider gastric lavage. Otherwise treatment is symptomatic and supportive.

Fire-fighting measures

Extinguishing Media and Procedure: Dry chemical, carbon dioxide, water spray or foam.

Use water spray to keep fire-exposed containers cool. Approach fire from upwind to avoid hazardous vapours and toxic decomposition products. Fight fire from protected location or maximum possible distance. Avoid heavy hose streams. Dike area to prevent water runoff. Firemen should wear self-contained breathing apparatus and protective clothing.

Hazardous Decomposition or Byproducts in a Fire: The essential breakdown products are carbon monoxide and carbon dioxide.

Accidental release measures

Personal Protection: Observe all protection and safety precautions when cleaning up spills. Depending on the magnitude of the spill this may mean wearing safety glasses or face mask, gloves and chemical resistant clothing.

Steps to Be Taken in Case of Spill: Stop the source of the spill immediately if safe to do so. Contain the spill to prevent any further contamination of surface, soil or water. Reduce and avoid formation of airborne dust as much as possible, if appropriate by moistening. Remove sources of ignition.

Spills on the floor or other impervious surface should be swept up immediately and placed in suitable containers. Rinse area with strong industrial detergent and much water. Absorb wash liquid with suitable inert absorbent such as Fuller’s earth, universal absorbent, bentonite or other absorbent clay and place contaminated absorbent in the same containers.

Spills in water should be contained as much as possible by isolation of the contaminated water. The contaminated water must be collected and removed for treatment or disposal.

Spills that soak into the ground should be dug up and placed in suitable containers.

The used containers should be marked. Any collected spill material, contaminated waste or absorbent must be disposed of in accordance with the instructions provided under Disposal.

Washings must be prevented from entering surface water drains.

Uncontrolled discharge into water courses must be alerted to the appropriate regulatory body.

The product may be disposed of through controlled incineration with flue gas scrubbing.

Handling and storage

Precautions to Be Taken in Handling: It is recommended to use the substance in a closed system with remote system control. When this is not possible, adequate ventilation or local exhaust ventilation is required to remove airborne dust.

Precautions to Be Taken in Storing: Store in a dry place in closed containers. Do not contaminate air, water or foodstuffs by storage or disposal.

Fire and Explosion Precautions: Like most organic solids, the substance must be expected to form explosive mixtures with air. Avoid dust formation and take precautionary measures against static discharge. Use explosion protected equipment. Keep away from sources of ignition.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

Not classified as hazadous material for transport

Shipping information

Proper shipping name and description:

Not applicable

Chemical name:

(1R,4R,5S)-4-Hydroxy-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one

Language:

English

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

Not classified as hazardous material for transport.

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

Not classified as hazardous material for transport.

Shipping information

Proper shipping name and description:

Not applicable

Chemical name:

(1R,4R,5S)-4-Hydroxy-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

Not classified as hazardous material for transport.

Shipping information

Proper shipping name and description:

Not applicable

Chemical name:

(1R,4R,5S)-4-Hydroxy-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one

Remarks

SpecialProvisions

Exposure controls / personal protection

Exposure Limit Values: No exposure limits have been established for this compound.

Personal Protection: When used in a closed system, personal protection equipment will not normally be required. The following is meant for other situations, when the use of a closed system is not possible, or in case of maintenance, repair, sampling, removal of foreign bodies, etc., or in case of spill. Consider the need to render equipment or piping systems nonhazardous before opening.

Respiratory Protection: Provide local exhaust ventilation system. Other respiratory protection will not normally be required because of low vapour pressure, but the inhalation of dust must be avoided, if required by using a face mask or officially approved respiratory protection equipment with a universal filter type including particle filter.

Protective Gloves : Wear chemical resistant gloves, such as barrier laminate, butyl rubber, nitrile rubber or viton. The breakthrough times of these materials for Biocartol are unknown, but it is expected that they will give adequate protection based on the low dermal toxicity of the substance.

Eye Protection: Wear safety glasses. It is recommended to provide an emergency eye wash fountain in the immediate working area.

Other Protection: Wear appropriate chemical resistant clothing.

Work/Hygienic Practices: Always wash hands, face and arms with water and soap before smoking, eating or drinking.

Stability and reactivity

Thermal Decomposition: Stable at ambient temperatures. Endothermal fusion starting from 105°C. Oxidizable from 125°C (in pure oxygen atmosphere). Decomposes from approx. 235°C.

Like for most organic powders, excessive dust formation may pose a dust explosion hazard.

Hazardous Decomposition or  Byproducts: The essential breakdown products are carbon monooxide and carbon dioxide.              

Materials to Avoid: The substance reacts with basic (caustic) materials in an acid-base neutralization reaction which can be hazardous because of heat release.

Disposal considerations

Waste Disposal Method: Left-over material collected from maintenance, cleaning, filtering of ventilation exhaust systems and other procedures can be removed by controlled discharge to a waste water treatment plant. Other possible methods of disposal are controlled incineration with flue gas scrubbing or removal to a licensed chemical destruction plant.

Do not contaminate water bodies by storage or disposal.

Container Disposal: Triple rinse (or equivalent). Then offer for reuse, recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill.

Disposal must always be in accordance with all applicable local regulations.