Registration Dossier
Registration Dossier
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EC number: 200-087-7 | CAS number: 51-28-5
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data have been obtained from secoundary source.
Data source
Referenceopen allclose all
- Reference Type:
- other: databank
- Title:
- Unnamed
- Year:
- 2 012
- Reference Type:
- other: original reference
- Title:
- "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure,"
- Author:
- Izmerov, N.F., et al.
- Year:
- 1 982
- Bibliographic source:
- 85GMAT , Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,62, 1982
Materials and methods
- Principles of method if other than guideline:
- The method has not been specified.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,4-dinitrophenol
- EC Number:
- 200-087-7
- EC Name:
- 2,4-dinitrophenol
- Cas Number:
- 51-28-5
- Molecular formula:
- C6H4N2O5
- IUPAC Name:
- 2,4-dinitrophenol
Constituent 1
Test animals
- Species:
- dog
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 30
- Remarks on duration:
- Months
- Concentrations:
- 300 mg/m3
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LCLo
- Effect level:
- 300 other: mg/m^3
- Remarks on result:
- other: Duration: 30 M (months)
Any other information on results incl. tables
The LCLo-Lowest published lethal concentration on dog of 2,4 -dinitrophenol is 300 mg/m3. Details of toxic effects have not been reported other than lethal dose value.
Applicant's summary and conclusion
- Conclusions:
- The LCLo-Lowest published lethal concentration on dog , tested in 30 Months of 2,4 -dinitrophenol is 300 mg/m^3. Details of toxic effects have not been reported other than lethal dose value.
- Executive summary:
Data have been obtained from secoundary source taht mentions 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,62,1982. The method has not been specified. The LCLo-Lowest published lethal concentration on dog of 2,4 -dinitrophenol is 300 mg/m3 for 30 months but details of toxic effects have not been reported other than lethal dose value.
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