Registration Dossier
Registration Dossier
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EC number: 284-957-1 | CAS number: 85005-25-0
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (56d) >= 1000 mg/kg dw (Eisenia fetida, OECD 222); read-across
Key value for chemical safety assessment
Additional information
Since no studies investigating the toxicity to soil macroorganisms of Fatty acids, C14-18 and C18-unsatd., branched and linear, esters with neopentyl glycol (CAS No. 85005-25-0) are available, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read across to the structurally similar category member 2,2-dimethyl-1,3-propanediyl dioleate (CAS No. 42222-50-4) was conducted. Further justification is given within the endpoint summary in IUCLID chapter 6.3 and within the category justification in IUCLID section 13.
The key study conducted with 2,2-dimethyl-1,3-propanediyl dioleate (CAS No. 42222-50-4) was performed according to OECD Guideline 222 and GLP (Amsel, 2013). The test organism Eisenia fetida was exposed to the nominal test concentrations of 62.5, 125, 250, 500 and 1000 mg/kg soil dw for 56 days. No significant effects on reproduction were observed during the study, and the NOEC was reported to be ≥ 1000 mg/kg dw.
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