Registreeritud ained

Registreeritud ained

Registreeritud ained

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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate
BENZYL THIQ TOSYLATE; PD 114683-10; TIC-B
406-960-0 77497-97-3 Active NONS Joint Tonnage data confidential 14-11-2011 View substance registered dossier
(S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate
BENZYL THIQ TOSYLATE; PD 114683-10; TIC-B
406-960-0 77497-97-3 Cease Manufacture Intermediate Individual Cease manufacture 04-10-2012 View substance registered dossier
(S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate
BENZYL THIQ TOSYLATE; PD 114683-10; TIC-B
406-960-0 77497-97-3 Active Intermediate Joint Intermediate use only 07-01-2020 View substance registered dossier
(S)-3-hydroxy-γ-butyrolactone
434-990-4 7331-52-4 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid
430-900-2 192725-50-1 Active Intermediate Joint Intermediate use only 14-06-2018 View substance registered dossier
(S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid
430-900-2 192725-50-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile
941-762-2 1297537-41-7 Active Intermediate Individual Intermediate use only 13-10-2017 View substance registered dossier
(S)-4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one
S EDIN; S TETRALONE
444-830-5 124379-29-9 Active Intermediate Joint Intermediate use only 31-03-2020 View substance registered dossier
(S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-770-7 128173-52-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-hydroxymethylbenzonitrile hemi(+)-di-toluoyltartrate
603-261-4 128173-53-5 Active Intermediate Joint Intermediate use only 11-05-2018 View substance registered dossier
(S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid
L-GLUTAMYL-HISTAMINE
421-900-3 169283-81-2 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
CAMPTOTHECIN
444-280-6 7689-03-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-4-methyloxazolidine-2,5-dione
218-750-4 2224-52-4 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
(S)-5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-ium benzenesulfonate
848-452-5 2097130-30-6 Active Full Joint ≥ 1 to < 10 tonnes 28-02-2021 View substance registered dossier
(S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene
LACTOFTALURO
410-940-7 60166-91-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide
941-760-1 1297537-33-7 Active Intermediate Individual Intermediate use only 04-01-2018 View substance registered dossier
(S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride
948-271-2 - Active Intermediate Joint Intermediate use only 09-07-2018 View substance registered dossier
(S)-5-fluoro-3-methylisobenzofuran-1(3H)-one
943-180-4 1803573-19-4 Active Intermediate Joint Intermediate use only 11-09-2019 View substance registered dossier
(S)-5-Methoxy-2-propionamidotetralin
607-376-0 244239-67-6 Active Intermediate Joint Intermediate use only 02-03-2018 View substance registered dossier
(S)-5-tert-butoxy-3-(tert-butyldimethylsilyloxy)-5-oxopentylboronic acid (+)-pinanediol ester
811-219-3 1681053-95-1 Active Intermediate Individual Intermediate use only 28-02-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 - View substance registered dossier
MAPIC Europe NV EXCELSIORLAAN 83 1930 ZAVENTEM Belgium Belgium Cease Manufacture (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 2019 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 2021 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 2017 View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (S)-3-benzyloxycarbonyl-1,2,3,4-tetrahydro-isoquinolinium 4-methylbenzenesulfonate 406-960-0 77497-97-3 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-3-hydroxy-γ-butyrolactone 434-990-4 7331-52-4 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid 430-900-2 192725-50-1 2011; 2018 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (S)-3-methyl-2-(2-oxotetrahydropyrimidine-1-yl)butyric acid 430-900-2 192725-50-1 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile 941-762-2 1297537-41-7 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (S)-4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one 444-830-5 124379-29-9 - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (S)-4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one 444-830-5 124379-29-9 2010; 2020 View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-770-7 128173-52-4 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (S)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-hydroxymethylbenzonitrile hemi(+)-di-toluoyltartrate 603-261-4 128173-53-5 2018 View substance registered dossier
- - - - (S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid 421-900-3 169283-81-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active (S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione 444-280-6 7689-03-4 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (S)-4-methyloxazolidine-2,5-dione 218-750-4 2224-52-4 - View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active (S)-5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-ium benzenesulfonate 848-452-5 2097130-30-6 - View substance registered dossier
bracco imaging Via Folli 50 20134 milan Italy Italy Active (S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene 410-940-7 60166-91-8 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active (S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide 941-760-1 1297537-33-7 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride 948-271-2 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (S)-5-fluoro-3-methylisobenzofuran-1(3H)-one 943-180-4 1803573-19-4 2019 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (S)-5-Methoxy-2-propionamidotetralin 607-376-0 244239-67-6 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-5-tert-butoxy-3-(tert-butyldimethylsilyloxy)-5-oxopentylboronic acid (+)-pinanediol ester 811-219-3 1681053-95-1 - View substance registered dossier

Andmed on võetud ECHA-le esitatud registreerimistoimikutest ja sorditud viimase ajakohastamise kuupäeva järgi. Üldkogusevahemiku andmed on koondatud kõikidest toimikutest, v.a kaks erandit: kogused, millele on taotletud konfidentsiaalsust, ja kogused, mida kasutatakse vaheainena erineva kemikaali tootmiseks. Avaldatud üldkogusevahemiku andmed ei kajasta tingimata registreeritud kogusevahemikke.

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