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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene
- - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
(17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol
- - Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
(1R)-2-[5-(2-halo-3-methoxyphenyl)-3-[2-halo-6-(trihalomethyl)benzyl]- 4-alkyl-2,6-dioxoheterocyclyl]-1-phenylethanaminium salicylate
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropanaminium (2S)-2-[(4-chlorobenzoyl)oxy]propanoate
- - Active Intermediate Joint Intermediate use only 14-11-2017 View substance registered dossier
(2S)-2-[(4-Chlorobenzoyl)oxy]propanoic acid
- - Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1)
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(3R)-4[(2.4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one
- - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one
- - Active Intermediate Joint Intermediate use only 14-03-2022 View substance registered dossier
(aminoalkyl) hydrogen thiosulfate
- - Active Full Joint ≥ 1 to < 10 tonnes 05-01-2021 View substance registered dossier
(E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide
- - Active Intermediate Individual Intermediate use only 08-11-2016 View substance registered dossier
(S)-1’- (tert-butyl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-carboxylic acid
- - Active Intermediate Joint Intermediate use only 30-03-2022 View substance registered dossier
(S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
.alpha.-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, compd. with 2-butyne-1,4-diol (1:1)
- 960404-59-5 Active Full Individual ≥ 10 to < 100 tonnes 14-03-2017 View substance registered dossier
.alpha.-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, compd. with 2-butyne-1,4-diol (1:1)
- 960404-59-5 Active Full Joint ≥ 10 to < 100 tonnes 17-06-2022 View substance registered dossier
.alpha.-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, compd. with 2-butyne-1,4-diol (1:1)
- 960404-59-5 Active Intermediate Joint Intermediate use only 10-12-2021 View substance registered dossier
1,1,1,2,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propoxy]propoxy]-3-(1,2,2,2-tetrafluoroethoxy)propane
- 37486-69-4 Active Full Individual ≥ 1 to < 10 tonnes 06-05-2019 View substance registered dossier
1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-15-[[(1,1-dimethylethoxy)carbonyl]amino]-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H) -carboxylic acid ethyl ester (2R,6S,12Z,13aS,14aR,16aS)
- - Active Intermediate Joint Intermediate use only 23-09-2013 View substance registered dossier
1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H)-carboxylic acid (2R,6S,12Z,13aS,14aR,16aS)
- - Active Intermediate Joint Intermediate use only 17-09-2013 View substance registered dossier
1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H)-carboxylic acid ethyl ester hydrochloride (2R,6S,12Z,13aS,14aR,16aS)
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives (upper limit: 41% w/w; typical concentration: 38% w/w)
- - Active Full Individual ≥ 0 to < 10 tonnes 24-01-2019 View substance registered dossier
1,2-Benzenediol, 3,5-dialkyl-, 1,2-dicarboxylate
- - Active Intermediate Joint Intermediate use only 05-06-2014 View substance registered dossier
1,3-Dichloro-1-propene containing 1,2,3-Trichloropropane (Medium grade)
- - Active Intermediate Individual Intermediate use only 09-05-2022 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene - - - View substance registered dossier
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol - - - View substance registered dossier
[Confidential] - - - (1R)-2-[5-(2-halo-3-methoxyphenyl)-3-[2-halo-6-(trihalomethyl)benzyl]- 4-alkyl-2,6-dioxoheterocyclyl]-1-phenylethanaminium salicylate - - - View substance registered dossier
a.c.r.a.f. s.p.a. via guardapasso 1 04011 aprilia Italy Italy Active (1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropanaminium (2S)-2-[(4-chlorobenzoyl)oxy]propanoate - - - View substance registered dossier
a.c.r.a.f. s.p.a. via guardapasso 1 04011 aprilia Italy Italy Active (2S)-2-[(4-Chlorobenzoyl)oxy]propanoic acid - - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid - - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1) - - - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R)-4[(2.4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one - - - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (6S)-1'-tert-butyl-3-chlorospiro[5,7-dihydrocyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-2'-one - - 2022 View substance registered dossier
RSI ChemRep Europe Ltd (S001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active (aminoalkyl) hydrogen thiosulfate - - 2017; 2021 View substance registered dossier
[Confidential] - - - (E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone - - - View substance registered dossier
[Confidential] - - - (E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one - - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide - - 2016 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (S)-1’- (tert-butyl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-carboxylic acid - - - View substance registered dossier
[Confidential] - - - (S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid - - - View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active .alpha.-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, compd. with 2-butyne-1,4-diol (1:1) - 960404-59-5 2014; 2017 View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active .alpha.-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, compd. with 2-butyne-1,4-diol (1:1) - 960404-59-5 2014; 2017; 2022 View substance registered dossier
AstraZeneca B 313:5 AZ GlobalSHE- Chem.Reg. 15185 Södertälje Sweden Sweden Active .alpha.-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, compd. with 2-butyne-1,4-diol (1:1) - 960404-59-5 - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active .alpha.-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, compd. with 2-butyne-1,4-diol (1:1) - 960404-59-5 2021 View substance registered dossier
[Confidential] - - - 1,1,1,2,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propoxy]propoxy]propoxy]-3-(1,2,2,2-tetrafluoroethoxy)propane - 37486-69-4 - View substance registered dossier
[Confidential] - - - 1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-15-[[(1,1-dimethylethoxy)carbonyl]amino]-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H) -carboxylic acid ethyl ester (2R,6S,12Z,13aS,14aR,16aS) - - - View substance registered dossier
[Confidential] - - - 1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H)-carboxylic acid (2R,6S,12Z,13aS,14aR,16aS) - - - View substance registered dossier
[Confidential] - - - 1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-heteromonocyclic)carbonyl]amino]-5,16-dioxo-2-(6-heteropolycyclicoxy)-alicyclic[e]heteromonocyclic[1,2-a][1,4]heteromonocycle-14a(5H)-carboxylic acid ethyl ester hydrochloride (2R,6S,12Z,13aS,14aR,16aS) - - - View substance registered dossier
Nouryon Functional Chemicals B.V. Velperweg 76 6824 BM Arnhem Netherlands Netherlands Active 1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives (upper limit: 41% w/w; typical concentration: 38% w/w) - - 2017; 2018; 2019 View substance registered dossier
[Confidential] - - - 1,2-Benzenediol, 3,5-dialkyl-, 1,2-dicarboxylate - - - View substance registered dossier
GRACE GmbH In der Hollerhecke 1 67545 Worms Germany Germany Active 1,2-Benzenediol, 3,5-dialkyl-, 1,2-dicarboxylate - - 2014 View substance registered dossier
INOVYN Deutschland GmbH Luwigstrasse 12 47495 Rheinberg Germany Germany Active 1,3-Dichloro-1-propene containing 1,2,3-Trichloropropane (Medium grade) - - - View substance registered dossier

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