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As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride
SULPHONAMIDO-ANILINE
406-010-5 88918-84-7 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride
816-907-7 1294454-93-5 Cease Manufacture Intermediate Joint Cease manufacture 28-05-2020 View substance registered dossier
(4-butoxy-2,3-difluorophenyl)boronic acid
692-793-0 156487-12-6 Active Full Joint ≥ 1 to < 10 tonnes 16-05-2018 View substance registered dossier
(4-carboxybutyl)triphenylphosphonium bromide
241-782-5 17814-85-6 Active Intermediate Joint Intermediate use only 20-07-2022 View substance registered dossier
(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone
695-300-7 1103738-30-2 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 No longer Valid Intermediate Individual No longer valid 13-11-2013 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 Active Intermediate Individual Intermediate use only 28-09-2010 View substance registered dossier
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid
826-639-2 1817776-86-5 Active Intermediate Joint Intermediate use only 20-07-2020 View substance registered dossier
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
SILANEOPHAN
405-020-7 105024-66-6 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride
SULPHAZINE
406-090-1 81880-96-8 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(4-methylphenyl)mesitylene sulfonate
KAYAKU TG-MC
407-530-5 67811-06-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-nitrophenyl)methanesulfonyl chloride
609-806-2 4025-75-6 Active Intermediate Individual Intermediate use only 18-12-2019 View substance registered dossier
(4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]
ENOL SULFOXIDE ESTER
411-820-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-nonylphenoxy)acetic acid
221-486-2 3115-49-9 Active Full Joint ≥ 100 to < 1 000 tonnes 04-07-2014 View substance registered dossier
(4-phenylbutyl)phosphinic acid
420-450-5 86552-32-1 Active Intermediate Joint Intermediate use only 09-12-2013 View substance registered dossier
(4-pyridylmethyl)amine
223-092-6 3731-53-1 Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
(4-pyridylthio)acetyl chloride hydrochloride
248-348-4 27230-51-9 Active Intermediate Joint Intermediate use only 25-10-2021 View substance registered dossier
(4-tert-butyl-2,6-dimethylphenyl)acetonitrile
284-183-4 84803-57-6 Active Intermediate Joint Intermediate use only 30-07-2015 View substance registered dossier
(4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate
453-050-4 - Active NONS Individual Tonnage data confidential 04-02-2011 View substance registered dossier
(4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)
700-867-1 - Active Full Joint ≥ 1 to < 10 tonnes 11-06-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride 406-010-5 88918-84-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride 406-010-5 88918-84-7 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (4-benzylpiperazin-1-yl)(cyclopropyl)methanone hydrochloride 816-907-7 1294454-93-5 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (4-butoxy-2,3-difluorophenyl)boronic acid 692-793-0 156487-12-6 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (4-carboxybutyl)triphenylphosphonium bromide 241-782-5 17814-85-6 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone 695-300-7 1103738-30-2 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone 695-300-7 1103738-30-2 2020 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (4-chlorophenyl)hydrazine 214-029-3 1073-69-4 2018 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (4-chlorophenyl)hydrazine 214-029-3 1073-69-4 2010 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid 826-639-2 1817776-86-5 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid 826-639-2 1817776-86-5 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane 405-020-7 105024-66-6 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Cease Manufacture (4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane 405-020-7 105024-66-6 2010 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride 406-090-1 81880-96-8 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-methylphenyl)mesitylene sulfonate 407-530-5 67811-06-7 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (4-nitrophenyl)methanesulfonyl chloride 609-806-2 4025-75-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] 411-820-7 - - View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Active (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 2014 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 - View substance registered dossier
Colors & Effects France S.A.S. Rue de la Chapelle 28 68330 Huningue France France Cease Manufacture (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 2015 View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (4-phenylbutyl)phosphinic acid 420-450-5 86552-32-1 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-phenylbutyl)phosphinic acid 420-450-5 86552-32-1 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (4-pyridylmethyl)amine 223-092-6 3731-53-1 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 2021 View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Active (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 - View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 2021 View substance registered dossier
CHEMSAFE srl on behalf of AZO INTERNATIONAL CHEMICAL ltd Via Ribes, 5 10010 Colleretto Giacosa TO Italy Italy Active (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (4-tert-butyl-2,6-dimethylphenyl)acetonitrile 284-183-4 84803-57-6 - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active (4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate 453-050-4 - 2011 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1) 700-867-1 - 2020 View substance registered dossier

Andmed on võetud ECHA-le esitatud registreerimistoimikutest ja sorditud viimase ajakohastamise kuupäeva järgi. Üldkogusevahemiku andmed on koondatud kõikidest toimikutest, v.a kaks erandit: kogused, millele on taotletud konfidentsiaalsust, ja kogused, mida kasutatakse vaheainena erineva kemikaali tootmiseks. Avaldatud üldkogusevahemiku andmed ei kajasta tingimata registreeritud kogusevahemikke.

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