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As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide
UK-88,861-04
421-810-4 194602-27-2 Active Intermediate Joint Intermediate use only 24-09-2010 View substance registered dossier
(S)-2,3-dihydro-1H-indole-2-carboxylic acid
[S]-2-INDOLINE CARBOXYLIC ACID
410-860-2 79815-20-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-2,3-dihydro-1H-indole-2-carboxylic acid
[S]-2-INDOLINE CARBOXYLIC ACID
410-860-2 79815-20-6 Active Intermediate Joint Intermediate use only 17-03-2014 View substance registered dossier
(S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
873-085-2 74844-93-2 Active Intermediate Joint Intermediate use only 01-06-2022 View substance registered dossier
(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride
942-180-1 - Cease Manufacture Intermediate Individual Cease manufacture 28-08-2015 View substance registered dossier
(S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid
951-381-3 - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
(S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide
824-341-7 357338-13-7 No longer Valid Full Individual No longer valid 02-10-2019 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 109425-51-6 Active NONS Joint Tonnage data confidential 17-08-2010 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 109425-51-6 Active Intermediate Individual Intermediate use only 07-02-2022 View substance registered dossier
(S)-2-acetamido-N-benzyl-3-methoxypropanamide
806-591-9 175481-37-5 Active Full Joint ≥ 10 to < 100 tonnes 09-02-2021 View substance registered dossier
(S)-2-amino-1,1-diphenyl 1-propanol
622-109-8 78603-91-5 Active Intermediate Individual Intermediate use only 30-11-2017 View substance registered dossier
(S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile monohydrochloride
219-823-3 2544-13-0 Cease Manufacture Intermediate Joint Cease manufacture 03-12-2013 View substance registered dossier
(S)-2-amino-5-methoxytetralin hydrochloride
611-645-8 58349-17-0 Active Intermediate Joint Intermediate use only 02-03-2018 View substance registered dossier
(S)-2-Amino-butylacetamide
615-935-5 7324-11-0 Active Intermediate Joint Intermediate use only 15-10-2019 View substance registered dossier
(S)-2-chloro-1-(3,4-difluorophenyl)ethan-1-ol
819-945-2 1006376-60-8 Active Intermediate Individual Intermediate use only 29-01-2018 View substance registered dossier
(S)-2-chloropropionic acid
L-2-CHLOROPROPIONIC ACID; L-2-CHLORPROPIONSÄURE
411-150-5 29617-66-1 Active Intermediate Joint Intermediate use only 24-03-2021 View substance registered dossier
(S)-2-chloropropionic acid
L-2-CHLOROPROPIONIC ACID; L-2-CHLORPROPIONSÄURE
411-150-5 29617-66-1 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
ECTOIN
431-910-1 96702-03-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
ECTOIN
431-910-1 96702-03-3 Active Full Joint ≥ 1 tonnes 19-08-2022 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 2010 View substance registered dossier
Zach System ZI La Croix Cadeau 49242 Avrillé France France Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
DSM Pharma Chemicals Venlo B.V. Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands Netherlands Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 69451 Lyon Cedex 06 France France Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 2013; 2014 View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 873-085-2 74844-93-2 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 873-085-2 74844-93-2 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride 942-180-1 - 2017 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid 951-381-3 - 2021 View substance registered dossier
[Confidential] - - - (S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid - - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (S)-2-(5-Oxo-3-propyl-1,2-dihydropyrrol-1-yl) butyramide 824-341-7 357338-13-7 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 109425-51-6 - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 109425-51-6 2019 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 109425-51-6 2019; 2020; 2022 View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active (S)-2-acetamido-N-benzyl-3-methoxypropanamide 806-591-9 175481-37-5 - View substance registered dossier
UCB Pharma S.A.(Belgium) Allée de la recherche, 60 1070 Brussels Belgium Belgium Active (S)-2-acetamido-N-benzyl-3-methoxypropanamide 806-591-9 175481-37-5 2019; 2021 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (S)-2-amino-1,1-diphenyl 1-propanol 622-109-8 78603-91-5 - View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Cease Manufacture (S)-2-amino-3-(3,4-dimethoxyphenyl)-2-methylpropiononitrile monohydrochloride 219-823-3 2544-13-0 2022 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (S)-2-amino-5-methoxytetralin hydrochloride 611-645-8 58349-17-0 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (S)-2-Amino-butylacetamide 615-935-5 7324-11-0 2019 View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (S)-2-Amino-butylacetamide 615-935-5 7324-11-0 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (S)-2-chloro-1-(3,4-difluorophenyl)ethan-1-ol 819-945-2 1006376-60-8 - View substance registered dossier
Nufarm GmbH & Co.KG OR St.-Peter-Str.25 4021 Linz Austria Austria Active (S)-2-chloropropionic acid 411-150-5 29617-66-1 2010; 2011; 2018; 2021 View substance registered dossier
CIECH Sarzyna Spółka Akcyjna ul. Chemikow 1 37-310 Nowa Sarzyna Podkarpackie Poland Poland Active (S)-2-chloropropionic acid 411-150-5 29617-66-1 - View substance registered dossier
D’Orland GmbH Kutschkergasse 42/16 1180 Vienna Austria Austria Active (S)-2-chloropropionic acid 411-150-5 29617-66-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-2-chloropropionic acid 411-150-5 29617-66-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 96702-03-3 - View substance registered dossier
B-Lands Consulting (811587-0) World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France France Active (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 96702-03-3 - View substance registered dossier
[Confidential] - - - (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 96702-03-3 - View substance registered dossier

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