Quaternary ammonium compounds, tri-C8-10-alkylmethyl, chlorides

Solubility in organic solvents / fat solubility

Link to relevant study record(s)

Reference

Endpoint:

solubility in organic solvents / fat solubility

Remarks:

Solubility in n-Octanol

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2021

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Principles of method if other than guideline:

The n-octanol solubility of substances with an expected high solubility is normally determined analogous to the flask method described in the OECD Guideline for the Testing of Chemicals
105 (determination of water solubility). To apply this method, the preparation of a saturated solution of test item in n-octanol is required. This is not feasible for test items with a very high or
complete solubility/miscibility, therefore, a homemade method described in the external method EM/00408/01 from Competence Center Analytics, BASF SE (chapter 4: visual method) was applied to investigate complete miscibility.
See also
https://en.wikipedia.org/wiki/Miscibility, retrieved 20th June 2021
Determination
Miscibility of two materials is often determined optically. When the two miscible liquids are combined, the resulting liquid is clear

GLP compliance:

no

Key result

Medium:

n-octanol

Solubility:

869

Temp.:

20 °C

Details on results:

The n-octanol solubility of the test item was determined to be > 99.9 g/100 g which equals a concentration of 869 g/L in relation to the total volume of the mixture
Therefrom, it was concluded that the test item is most probably miscible with n-octanol at room temperature (T = 23 °C) and at T = 20.0 °C ± 0.5 °C in any ratio.
Details refer to the attached fully study report

Conclusions:

The n-octanol solubility of the test item was determined to be > 99.9 g/100 g which equals a concentration of 869 g/L in relation to the total volume of the mixture
Therefrom, it was concluded that the test item is most probably miscible with n-octanol at room temperature (T = 23 °C) and at T = 20.0 °C ± 0.5 °C in any ratio.

Description of key information

Solubility in n-Octanol= 869 g/L at 20°C

Additional information

The n-octanol solubility of the test item was determined to be > 99.9 g/100 g which equals a concentration of 869 g/L in
relation to the total volume of the mixture
Therefrom, it was concluded that the test item is most probably miscible with n-octanol at room temperature (T = 23 °C) and at T = 20.0 °C ± 0.5 °C in any ratio.