Barium chromate

Toxicity to microorganisms

Administrative data

Endpoint:

toxicity to microorganisms, other

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remarks'

Remarks:

The EU RAR summarises the results of a number of studies which individually have limitations regarding study design and reliability. However, the results of these studies when taken as a whole, provide an adequate assessment of toxicity to micro-organisms. The data are considered to fulfil the criteria laid down in Annex XI to Regulation 1907/2006: adequate for classification and labelling, adequate coverage of key parameters (inhibition), exposure duration comparable or longer that Article 13(3) methods, adequate documentation provided: EU RAR, of which parts have been copied to this endpoint record. Reliability for endpoint also increased based on test results from several species.

Data source

Reference

Reference Type:

review article or handbook

Title:

Unnamed

Year:

2005

Materials and methods

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

Several studies reported with different methods.

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

Chromium

EC Number:

231-157-5

EC Name:

Chromium

Cas Number:

7440-47-3

Molecular formula:

Cr

IUPAC Name:

chromium

Sampling and analysis

Details on sampling:

Range of sampling methods

Test solutions

Details on test solutions:

Range of test solutions

Test organisms

Test organisms (species):

other: range of microbes reported

Test conditions

Hardness:

Data from different tests reported

Test temperature:

Data from different tests reported

pH:

Data from different tests reported

Dissolved oxygen:

Data from different tests reported

Details on test conditions:

Data from different tests reported

Results and discussion

Effect concentrations

Duration:

24 h

Dose descriptor:

NOEC

Effect conc.:

>= 0.26 mg/L

Any other information on results incl. tables

BACTERIA
Activated sludge	Chromium hydroxide sulphate	ISO 8192 - Inhibition of oxygen consumption	3h-NOEC >3,130	IUCLID, 1999
Azobacter vinelandii(soil bacterium)	Chromic chloride	Growth inhibition over 4 days	LOEC/NOEC ~ 0.26	Ueda et al, 1988
Fusarium oxysporum(soil fungus)	Chromic chloride	Growth inhibition over 27 hours	NOEC > 6.5	Ueda et al, 1988
Pseudomonas fluorescens	Dichromium trioxide		24h-NOEC >6,840	IUCLID, 1999
Pseudomonas fluorescens	Chromium hydroxide sulphate		24h-NOEC >313	IUCLID, 1999

Applicant's summary and conclusion

Conclusions:

Several studies have been conducted on several test materials which have been collected in the EU RAR.