tert-butyl isocyanate

Guidance on Safe Use

First-aid measures

Description of first aid measures

Inhalation:Get medical attention immediately. Move exposed person to fresh air. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep person warm and at rest. If not breathing, if  breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours. In the event of any complaints or symptoms, avoid further exposure.

Ingestion:Get medical attention immediately. Wash out mouth with water. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Chemical burns must be treated promptly by a physician. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Skin Contact:Get medical attention immediately. Remove contaminated clothing and shoes. Wash the skin immediately with plenty of soap and water; cleaning immediately with polyethyleneglycol 400 and washing subsequently with plenty of soap and water would be more effective. Wash skin immediately with plenty of soap and water even when contact with the product is suspected. Chemical burns must be treated promptly by a physician. Wash clothing before reuse. Clean shoes thoroughly before reuse.

Eye Contact:Get medical attention immediately. Immediately flush eyes with

plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Continue to rinse for at least 10 minutes. Chemical burns must be treated promptly by a physician.

Indication of any immediate medical attention and special treatment needed

Notes to physician:Basic aid, decontamination, symptomatic treatment. Treat with a

corticoid metered aerosol depending on the amount inhaled. If appropriate symptoms occur or inhalation of large quantities is suspected, administer cortisone intravenously in addition Medical surveillance for at least 48 hours.

Fire-fighting measures

Extinguishing media

Suitable extinguishing media       : In case of fire, use water spray (fog), foam, dry chemical or CO2.

Unsuitable extinguishing media :Do not use water jet.

Special hazards arising from the substance or mixture

Hazards from the substance or mixture:

Highly flammable liquid. In a fire or if heated, a pressure increase will occur and the container may burst, with the risk of a subsequent explosion.

Runoff to sewer may create fire or explosion hazard.

Hazardous combustion products:

Decomposition products may include the following materials: carbon oxides; nitrogen oxides; hydrogen cyanide

Advice for firefighters

Special precautions for firefighters:

Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. Move containers from fire area if this can be done without risk. Use water spray to keep fire-exposed containers cool. This material is harmful to aquatic organisms. Fire water contaminated with this material must be contained and prevented from being discharged to any waterway, sewer or drain.

Special protective equipment for fire-fighters:

Fire-fighters should wear appropriate protective equipment and self¬contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Remark:

The vapours are heavier than air and creep at ground level. If they are ignited, the flame may cover large distances.

Accidental release measures

Personal precautions,protective equipment and emergency procedures:

No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilt material. Shut off all ignition sources. No flares, smoking or flames in hazard area. Avoid breathing vapour or mist. Provide adequate ventilation. Put on appropriate personal protective equipment.

Environmental       precautions:

Avoid dispersal of spilt material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Methods and materials for containment and cleaning up:

Small Spill:

Stop leak if without risk. Use spark-proof tools and explosion-proof equipment. Take up with a moist, liquid-binding material (e.g. sand, sawdust or chemical binder based on hydrated calcium silicate) and treat carefully with diluted ammonia solution. Do not firmly seal waste containers (risk of CO2 generation!). Once the reaction is fully complete, pass on to disposal facilities. Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilt product.

Large Spill:

Stop leak if without risk. Prevent entry into sewers, water courses, basements or confined areas. Use spark-proof tools and explosion¬proof equipment. Collect spillage. Absorb with an inert material and place in an appropriate waste disposal container. Do not firmly seal waste containers (risk of CO2 generation!). Dispose of via a licensed waste disposal contractor. Carefully decompose residues with an aqueous ammonia solution.

Handling and storage

Precautions for safe handling:

Put on appropriate personal protective equipment (see Section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Persons with a history of skin sensitisation problems or asthma, allergies or chronic or recurrent respiratory disease should not be employed in any process in which this product is used. Do not get in eyes or on skin or clothing. Do not breathe vapour or mist. Do not ingest. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Do not enter storage areas and confined spaces unless adequately ventilated. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Store and use away from heat, sparks, open flame or any other ignition source. Use explosion¬proof electrical (ventilating, lighting and material handling) equipment. Use non-sparking tools. Take precautionary measures against electrostatic discharges. To avoid fire or explosion, dissipate static electricity during transfer by earthing and bonding containers and equipment before transferring material. Empty containers retain product residue and can be hazardous. The product is registered with strictly controlled conditions as defined in Article 17(3) or 18(4) of regulation (EC) no. 1907/2006 (REACH Regulation) and must therefore be handled as such. Refer to the industry guidance prepared by Concawe/Cefic/EFCG for advice on the confirmation of strictly controlled conditions.

Conditions for safe storage, including any incompatibilities:

Store in accordance with local regulations. Store in a segregated and approved area. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Eliminate all ignition sources. Separate from oxidizing materials. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabelled containers. Use appropriate containment to avoid environmental contamination.

Remarks       : Ensure effective ventilation. Make sure all pipelines, tanks and

equipment are leakproof. Vent waste air only via suitable separators or scrubbers.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

UN2484

Shipping

Labels:

Flammable, Toxic

Special provisions / remarks

Special provisions:

Hazard identification number
663
Limited quantity
LQ0

Inland waterway transport (UN RTDG/ADN(R))

UN number:

UN2484

Shipping

Labels:

Flammable, Toxic

Special provisions / remarks

Remarks:

Hazard
identification
number
663
Limited quantity
LQ0

Marine transport (UN RTDG/IMDG)

UN number:

UN2484

Shipping information

Proper shipping name and description:

not applicable

Chemical name:

not applicable

Labels:

Flammable, Toxic

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

--

Shipping information

Proper shipping name and description:

--

Chemical name:

--

Labels:

__

Special provisions / remarks

Remarks:

forbidden

Additional transport information

Additional information

Special provisions / remarks / other:

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code : Not available.

Hazard notes:
Toxic.
Highly flammable.
Flash point (Closed cup): -6°C
Corrosive.
Keep dry.
Pungent smelling.
Keep away from foodstuffs, acids and alkalis.

Exposure controls / personal protection

Control parameters

Ingredient name       Occupational exposure limits

tert-Butyl isocyanate       ARW (Europe).

                                                  internal value for the maximum workplace concentration

                                                     (WEL) TWA: 0,02 mg/m3, (NCO) 8 hour(s). STEL: 0,02 mg/m3, (NCO), 1 times per shift, 15 minute(s).

1,2-dichlorobenzene       EU OEL (Europe, 12/2009). Absorbed through skin.

                                                    TWA: 20 ppm 8 hour(s).

                                                    TWA: 122 mg/m3 8 hour(s).

                                                    STEL:  50 ppm 15 minute(s).

                                                    STEL: 306 mg/m3 15 minute(s).

                                                   

                                                   

Derived effect levels

Ingredient name                         Type                          Exposure                             Value                                   Population         Effects      

1,2-dichlorobenzene        DNEL                        Short term Inhalation           244 mg/m3                      Workers       Systemic

                                                     DNEL                         Long term Inhalation              59 mg/m3                       Workers       Systemic

                                                     DNEL                         Short term Dermal                 23 mg/kg bw/day          Workers       Systemic

                                                     DNEL                          Long term Dermal                4 mg/kg bw/day              Workers       Systemic

Conclusion: Not available.       

Predicted effect concentrations

Ingredient name                         Type                          Exposure                             Value                                   Population         Effects      

1,2-dichlorobenzene        DNEL                        Soil                                         0,0333 mg/kg dwt              Workers       Systemic

                                                     DNEL                        Sewage Treatment Plant         4,7 mg/l                           Workers       Systemic

                                                     DNEL                         Sediment                               0,1002 mg/kg dwt             Workers       Systemic

                                                     DNEL                          Fresh Waterl                          0,0037 mg/l                      Workers       Systemic

                                                     

Recommended monitoring procedures

   : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective equipment. Reference should be made to European Standard EN 689 for methods for the assessment of exposure by inhalation to chemical agents and national guidance documents for methods for   the determination of hazardous substances.

                                                 

Exposure controls

Risk management measures  

Occupational exposure controls

Technical measures:Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits. The engineering controls also need to keep gas, vapour or dust concentrations below any lower explosive limits. Use explosion-proof ventilation equipment.

Personal protection measures

Respiratory protection:

Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is

necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator.Recommended: Full mask with type ABEK filter if product forms vapours . If larger quantities escape, self-contained breathing apparatus must be used.

Hand protection:

Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. After contamination with product change the gloves immediately and dispose of them according to relevant national and local regulations Recommended: (< 1 hour) Polychloroprene - CR, Fluorinated rubber - FKM, Polyvinyl chloride - PVC

Eye-Protection:

Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts.Recommended: Tightly fitting safety goggles.

Skin Protection:

Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. Recommended: chemical-resistant protective suit.

Hygiene measures:

Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Environmental exposure controls

Technical measures:

Emissions from ventilation or work process equipment should be

checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels

      

      

Stability and reactivity

Reactivity       : No specific test data related to reactivity available for this product or

its ingredients.

Chemical stability       : Hazardous polymerization may occur under certain conditions of

storage or use.

Possibility of hazardous : Hazardous reactions or instability may occur under certain conditions

reactions       of storage or use.

Conditions to avoid       :Reactive with water, alcohols, acids, alkalis and amines. With water (in a closed container), pressure will increase and create a risk of bursting. Do not pressurise, cut, weld, braze, solder, drill, grind or expose containers to heat or sources of ignition.

Incompatible materials       :Highly reactive or incompatible with the following materials: oxidizing materials

Hazardous decomposition products:

Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Disposal considerations

Waste treatment methods

Product

Methods of disposal       

Examine possibilities for re-utilisation. Product residues and uncleaned empty containers should be packaged, sealed, labelled, and disposed of or recycled according to relevant national and local regulations. Where large quantities are concerned, consult the supplier. When uncleaned empty containers are passed on, the recipient must be warned of any possible hazard that may be caused by residues. For disposal within the EC, the appropriate code according to the European Waste List (EWL) should be used. It is among the tasks of the polluter to assign the waste to waste codes specific to industrial sectors and processes according to the European Waste List (EWL).

Hazardous waste

The classification of the product may meet the criteria for a hazardous waste.

Packaging

Methods of disposal

The generation of waste should be avoided or minimised wherever possible. Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible

Special precautions:

This material and its container must be disposed of in a safe way. Care should be taken when handling emptied containers that have not been cleaned or rinsed out. Empty containers or liners may retain some product residues. Vapor from product residues may create a highly flammable or explosive atmosphere inside the container. Do not cut, weld or grind used containers unless they have been cleaned thoroughly internally. Avoid dispersal of spilt material and runoff and contact with soil, waterways, drains and sewers.