3-methylpent-1-en-3-ol

Toxicity to microorganisms

Administrative data

Endpoint:

toxicity to microorganisms

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: A single species (Pseudomonas putida) instead of activated sludge from a non-adapted source was used in the study. Scientifically acceptable.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1988

Report date:

1988

Materials and methods

Principles of method if other than guideline:

The Growth inhibition test according to Brinkmann & Kühn, 1986 was the precurser of the German national test guideline DIN 38412, part 8

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2-methylbut-3-en-2-ol

EC Number:

204-068-4

EC Name:

2-methylbut-3-en-2-ol

Cas Number:

115-18-4

Molecular formula:

C5H10O

IUPAC Name:

2-methylbut-3-en-2-ol

Details on test material:

- Name of test material (as cited in study report): 2-methylbuten-3-ol-2
no further details given

Sampling and analysis

Analytical monitoring:

no

Test solutions

Details on test solutions:

Concentration of stock solution: 12500 mg/L

Test organisms

Test organisms (species):

Pseudomonas putida

Details on inoculum:

- Laboratory culture: Pseudomonas putida, DSM 50026

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

17 h

Test conditions

Nominal and measured concentrations:

Nominal test concentrations: control, 2500, 5000, 7500 and 10000 mg/L.

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

17 h

Dose descriptor:

EC10

Effect conc.:

6 260 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth inhibition

Effect concentrations 2

Duration:

17 h

Dose descriptor:

EC50

Effect conc.:

9 010 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth inhibition

Effect concentrations 3

Duration:

17 h

Dose descriptor:

other: EC90

Effect conc.:

> 10 000 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

growth inhibition

Any other information on results incl. tables

Change in the oxygen consuption rate of the test substance if compared to  the control:

test 
concentration
(mg/L)          % of control
5000               107.7
7500               72.5
10000              35.3