Chlorocresol

Short-term toxicity to fish

Description of key information

The 96 hour LC50 value of chlorocresol in Poecilia reticulata was found to be 6.71 mg/L. But the BCF value of chlorocresol reported was not >= 2000 as well as the substance was found to be rapidly degradable. Thus according to CLP criteria of aquatic classification it is concluded that the substance chlorocresol is not toxic to fish Poecilia reticulata.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

6.71 mg/L

Additional information

Based on the various studies available with Klimish rating 2 and 4 for the target substance CAS NO 59-50-7 .The results is summarized as follows

 

Sr.No	Endpoint	Effect values	Basis for effects	Duration	Species	Remarks
1	LC50	6.71 mg/l	mortality	96 hrs	Poecilia reticulata	Data from publication for target chemical
2	LC50	7.56 mg/l	mortality	96 hrs	Pimephales promelas	Data from publication for target chemical
3	LC50	2.2 mg/l	mortality	24 hrs	Poecilia reticulata	Data from publication for target chemical
4	LC50	1 – 3.5 mg/l	mortality	24 hrs	Danio rerio	Data from publication for target chemical

 

By applying weight of evidence approach to the studies summarized in the above table it can be observed that the LC50 values was found to be in range of 1 to 7.56 mg/l in 96 hrs and 24 hrs on the basis of mortality effect . But the BCF value of chlorocresol reported was not >= 2000 as well as the substance was found to be rapidly degradable. Thus according to CLP criteria of aquatic classification it is concluded that the substance chlorocresol is not toxic to fish (Poecilia reticulata, Pimephales promelas,Danio rerio).

However, since this chemical has a harmonized classification as "Aquatic acute 1 " category, for the pupose of chemical safety assessment, this classification shall be considered