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Lista de sustancias del anexo III

Lista de sustancias del anexo III

ECHA koostas registri ainetest, mis tõenäoliselt vastavad REACH-määruse III lisa kriteeriumidele. Eesmärk on aidata registreerijatel teha kindlaks, kas nõutavad on teabele esitatavad vähendatud miinimumnõuded või VII lisa täielikud andmed.

Registri koostamisel kasutati avalikult kättesaadavate andmebaaside katseandmeid ja (Q)SAR-mudeli tulemusi. Ohtlike toksikoloogiliste ja ökotoksikoloogiliste omaduste ning kasutusalade teavet, samuti muud seotud teavet tuleb võrrelda III lisa kriteeriumidega.

Kui aine ei ole selles loetelus, ei pruugi see tähendada, et aine ei vasta III lisa kriteeriumidele. Samamoodi kui aine on selles registris, saab registreerija siiski kasutada teabele esitatavaid vähendatud nõudeid, kui see on põhjendatud.

NB! Andmik ei ole klassifitseerimisvahend, vaid pakub teavet võimalike ohunäitajate kohta. Näiteks ei tähenda märge „potentsiaalne mutageen", et ECHA liigitab aine mutageenseks. Klassifitseerimisvajaduse kindlakstegemisel tuleb arvesse võtta kõiki tõendeid.

Download the full Annex III Inventory

You can download the full Annex III inventory as XLS format.

Download Annex III Inventory

 

1,6-bis(2,3-epoxypropoxy)hexane

EC / List no.: 240-260-4 CAS no.: 16096-31-4
Information source
# Suspected carcinogen: The Toolbox profiler 'Carcinogenicity (genotox and nongenotox) alerts by ISS' gives an alert for carcinogenicity # Suspected hazardous to the aquatic environment: Fish toxicity classification (SarPy/IRFMN) model in VEGA (Q)SAR platform predicts that the chemical is 'Toxic-2 (between 1 and 10 mg/l) (good reliability)'; Fish Acute Toxicity model (KNN/Read-Across) in VEGA (Q)SAR platform predicts that the chemical has a 96h LC50 of 7.31 mg/L (moderate reliability);The Danish QSAR database contains information indicating that the substance has a 48h EC50 to Daphnia of 61.86 mg/L # Suspected mutagen: The Toolbox profiler 'DNA alerts for AMES, MN and CA by OASIS v.1.3' gives an alert for mutagenicity; The Toolbox profiler 'in vitro mutagenicity (Ames test) alerts by ISS' gives an alert for mutagenicity; CAESAR Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (good reliability); ISS Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (moderate reliability); KNN Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (moderate reliability); SARPY Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is Mutagen (good reliability) # Suspected persistent in the environment: The Danish QSAR database contains information indicating that the substance is predicted as non readily biodegradable # Suspected respiratory sensitiser: The Toolbox profiler 'Respiratory sensitisation' gives an alert for respiratory sensitisation # Suspected skin irritant: The Danish QSAR database contains information indicating that the substance is predicted as skin irritant # Suspected skin sensitiser: The Toolbox profiler 'Protein binding alerts for skin sensitization by OASIS v1.3' gives an alert for skin sensitisation; CAESAR skin sensitisation model in VEGA (Q)SAR platform predicts that the chemical is Sensitizer (good reliability) # Suspected toxic for reproduction: The Toolbox profiler 'DART scheme v.1.0' gives an alert for toxicity to reproduction;CAESAR developmental toxicity model in VEGA (Q)SAR platform predicts that the chemical is Toxicant (moderate reliability)

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