Registration Dossier

Administrative data

Endpoint:
adsorption / desorption: screening
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2013

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
calculated with EUSES 2.1 (QSAR for organic acids) by using log pow of 3.6
GLP compliance:
no
Type of method:
other: calculation

Test material

Constituent 1
Reference substance name:
(Pentapropenyl succinimido)-caproic acid
IUPAC Name:
(Pentapropenyl succinimido)-caproic acid
Constituent 2
Chemical structure
Reference substance name:
6-[3-(C12-C18)-alkenyl(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid
EC Number:
701-162-1
Molecular formula:
C22H37NO4 - C28H49NO4
IUPAC Name:
6-[3-(C12-C18)-alkenyl(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid

Study design

Batch equilibrium or other method

Computational methods:
calculated with EUSES 2.1 (QSAR for organic acids) by using log pow of 3.6

Results and discussion

Adsorption coefficientopen allclose all
Type:
Koc
Value:
162 L/kg
Type:
Kd
Value:
3.3 L/kg
Matrix:
soil
% Org. carbon:
2
Type:
Kd
Value:
8.1 L/kg
Matrix:
sediment
% Org. carbon:
5
Type:
Kd
Value:
60 L/kg
Matrix:
activated sludge
% Org. carbon:
10

Applicant's summary and conclusion

Conclusions:
The registration substance has a measured Log Kow of 3.6 and based on this value the Exposure Modelling Program EUSES 2.1 calculates a Koc of 162 L/kg (QSAR for organic acids) corresponding to a Kd soil of 3.3 L/kg, Kd sediment of 8.1 L/kg and Kd activated sludge of 60 L/kg. These Kd values are low which means that an Adsorption / Desorption study is not warranted.
Executive summary:

The registration substance has a measured Log Kow of 3.6 and based on this value the Exposure Modelling Program EUSES 2.1 calculates a Koc of 162 L/kg (QSAR for organic acids) corresponding to a Kd soil of 3.3 L/kg, Kd sediment of 8.1 L/kg and Kd activated sludge of 60 L/kg. These Kd values are low which means that an Adsorption / Desorption study is not warranted.