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EC number: 204-541-5 | CAS number: 122-40-7
Endpoint summary
Administrative data
Description of key information
Biodegradation in water
Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7) under aerobic conditions (A. M. Api et. al, 2015).The study was performed according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test). Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. Aniline was used as a reference substance for the study. Test vessel involve theBottle 1 & 2: Basal culture medium + activated sludge 30 mg/l + test chemical (100 mg/l); Bottle 3: Basal culture medium + activated sludge 30mg/l+ aniline (100mg/l) and Bottle 4: Basal culture medium + activated sludge 30 mg/l. Reference substance undergoes 61% degradation in 28 days.The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanalwas determined to be 90% by BOD parameter in 28 days.Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
Biodegradation in water and sediment
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound (2E)-2-(phenylmethylidene)heptanal (CAS No: 122-40-7). If released in to the environment, 24.5% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of (2E)-2-(phenylmethylidene)heptanal in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical (2E)-2 -(phenyl methylidene)heptanal is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of (2E)-2-(phenylmethylidene)heptanal in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.625%), indicates that test chemical (2E)-2-(phenylmethylidene)heptanal is not persistent in sediment.
Biodegradation in soil
The half-life period of test chemical (2E)-2-(phenylmethylidene)heptanal (CAS No: 122-40-7) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 74.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of (2E)-2-(phenylmethylidene)heptanal in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical (2E)-2-(phenylmethylidene)heptanal, it is concluded that the chemical (2E)-2-(phenylmethylidene)heptanal is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
Additional information
Biodegradation in water
Various experimental studies for the target compound (2E)-2 -(phenylmethylidene)heptanal (CAS No. 122-40-7) were reviewed for the biodegradation end point which are summarized as below:
In an experimental key study from peer reviewed journal (A. M. Api et. al, 2015), biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7) under aerobic conditions. The study was performed according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test). Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. Aniline was used as a reference substance for the study. Test vessel involve the Bottle 1 & 2: Basal culture medium + activated sludge 30 mg/l + test chemical (100 mg/l); Bottle 3: Basal culture medium + activated sludge 30mg/l+ aniline (100mg/l) and Bottle 4: Basal culture medium + activated sludge 30 mg/l. Reference substance undergoes 61% degradation in 28 days. The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanel was determined to be 90% by BOD parameter in 28 days.Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
In an supporting study from authoritative database (J-CHECK, 2017), biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7).The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)). Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanal was determined to be 51 and 81% by BOD and TOC removal parameter in 28 days. Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
Another biodegradation study was conducted according to OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test) under aerobic condition for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7) (HSDB, 2017). Secondary effluent from an unacclimatized activated sludge was used as a test inoculum. 10-day window criteria has been fulfilled. The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanal was determined to be 10 and 65% by CO2 evolution parameter after 10 and 28 days, respectively. Thus, based on percentage degradation, (2E)-2-(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
In an supporting study from peer reviewed journal (A.M. Api et. al, 2015),biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7). The study was performed according to OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test). The percentage degradation of test substance (2E)-2 -(phenylmethylidene) heptanal was determined to be 70.5% by CO2 evolution parameter in 28 days. Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
For the target chemical(2E)-2-(phenylmethylidene)heptanal(CAS No. 122-40-7), Biodegradation study was conducted according to Commission Directive 79/831/EWG annex V part C method for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (A.M. Api et. al, 2015). The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanal was determined to be41% in 28 days. Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be inherently biodegradable in nature.
On the basis of above results for target chemical (2E)-2 -(phenylmethylidene)heptanal (from peer reviewed journal, authoritative database J-CHECK and HSDB, 2017), it can be concluded that the test substance (2E)-2 -(phenylmethylidene)heptanal can be expected to be readily biodegradable in nature.
Biodegradation in water and sediment
Various predicted data for the target compound (2E)-2 -(phenylmethylidene)heptanal (CAS No. 122-40-7) were reviewed for the biodegradation in water and sediment end point which are summarized as below:
In aprediction done using the Mackay fugacity model level III of Estimation Programs Interface (EPI Suite, 2017) was run to predict the half-life in water and sediment for the test compound (2E)-2-(phenylmethylidene)heptanal (CAS No: 122-40-7). If released in to the environment, 24.5% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of (2E)-2-(phenylmethylidene)heptanal in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical (2E)-2 -(phenyl methylidene)heptanal is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of (2E)-2-(phenylmethylidene)heptanal in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.625%), indicates that test chemical (2E)-2-(phenylmethylidene)heptanal is not persistent in sediment.
In a supporting study from secondary source (Robust Summaries & Test Plans: Cinnamyl Derivatives: Revised Summaries, 2005), half-life of the chemical (2E)-2 -(phenylmethylide ne)heptanal (CAS No: 122-40-7) in water and sediment was estimated by using Mackay EQC Fugacity Level III. The following values has been used in the Mackay EQC Fugacity Level III for the estimating the half-life value. They are water solubility: 8.5 mg/l, vapour pressure: 0.0012 mm Hg, log Kow: 4.7 and melting point: 80°C, repsecitvely. If released into the environment, 32.6% of the chemical will partition into water according to the Mackay EQC Fugacity Level III and the half-life period of (2E)-2 -(phenylmethylidene)heptanal in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by Mackay EQC Fugacity Level III) indicates that the chemical (2E)-2 -(phenyl methylidene)heptanal is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of (2E)-2-(phenylmethylidene)heptanal in sediment is estimated to be 58.33 days (1400 hrs). Based on this half-life value of test chemical (2E)-2-(phenylmethylidene)heptanal, it is concluded that the chemical (2E)-2-(phenylmethylidene)heptanal is not persistent in the sediment environment and the exposure risk to soil dwelling animals is moderate to low.
On the basis of above results for target chemical (2E)-2 -(phenylmethylidene)heptanal (from EPI suite, 2017 and secondary source), it can be concluded that the test substance (2E)-2 -(phenylmethylidene)heptanal is not persistent in the water and sediment environment and therefore the exposure risk to aquatic and soil dwelling animals is moderate to low.
Biodegradation in soil
Various predicted data for the target compound (2E)-2-(phenylmethylidene)heptanal (CAS No. 122-40-7) were reviewed for the biodegradation in soil end point which are summarized as below:
The half-life period of test chemical (2E)-2-(phenylmethylidene)heptanal (CAS No: 122-40-7) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 74.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of (2E)-2-(phenylmethylidene)heptanal in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical (2E)-2-(phenylmethylidene)heptanal, it is concluded that the chemical (2E)-2-(phenylmethylidene)heptanal is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
In a supporting study from secondary source (Robust Summaries & Test Plans: Cinnamyl Derivatives: Revised Summaries, 2005),half-life of the chemical (2E)-2 -(phenylmethylid ene)heptanal (CAS No: 122 -40 -7) in soil was estimated by using Mackay EQC Fugacity Level III. The following values has been used in the Mackay EQC Fugacity Level III for the estimating the half-life value. They are water solubility: 8.5 mg/l, vapour pressure: 0.0012 mm Hg, log Kow: 4.7 and melting point: 80°C, repsecitvely. If released into the environment, 57.3% of the chemical will partition into soil according to the Mackay EQC Fugacity Level III. The half-life period of (2E)-2 -(phenylmethylidene)heptanal in soil is estimated to be 15 days (360 hrs). Based on this half-life value of test chemical (2E)-2 -(phenylmethylidene)heptanal, it is concluded that the chemical (2E)-2 -(phenylmethylidene)heptanal is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
On the basis of above results for target chemical(2E)-2-(phenylmethylidene)heptanal(from EPI suite, 2017 and secondary source), it can be concluded that the test substance (2E)-2 -(phenylmethylidene)heptanalis not persistent in the soil environment and therefore the exposure risk to soil dwelling animals is moderate to low.
On the basis of available information, the test substance (2E)-2 -(phenylmethylidene)heptanal can be considered to be readily biodegradable in nature.
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