Registration Dossier
Registration Dossier
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EC number: 701-118-1 | CAS number: 2156592-54-8
Endpoint summary
Administrative data
Description of key information
Additional information
SPECIATION OF THE REGISTRATION SUBSTANCE
The registration substance is a monobasic acid with a pKa of 4.7 (see IUCLID Chapter 4.21). This means that in aqueous medium at pH 7 >99% exists as salt.
REGISTRATION SUBSTANCE AND READ-ACROSS
The registration substance Tetrapropenyl succinimido caproic acid (Tetra-PSCA), CAS No. 1424148-99-1 is a structural homologue of Pentapropenyl succinimido caproic acid (Penta-PSCA), CAS No. 1424148-94-6. Both substance are not only structurally very similar they also have a similar Octanol-water partitioning coefficient: Tetra-PSCA Log Kow=3.7 and Penta-PSCA Log Kow=3.6. Assuming a narcotic mode of action the ecotoxicity of both substances should be comparable based on their comparable Log Kow. Both substances have also comparable vapour pressures and Critical Micelle Concentrations. Therefore it is justified to use substance data from Penta-PSCA for read-across to Tetra-PSCA.
In the table below the available acute and chronic ecotoxicity data for all three trophic levels are given for the read-across substance Penta-PSCA:
| Test | Guideline | Endpoint | Value |
| (mg/L) | |||
| Acute Fish | 203 | LC50 (96h) | 100 |
| Acute Daphnia | 202 | EC50 (48h) | 2.6 |
| Algae | 201 | ErC50 (72h) | 38 |
| Microorganisms | 209 | NOEC (3h) | 1000 |
| Chronic Daphnia | 202 | EC10 repro(21d) | 1.7 |
| Algae | 201 | ErC10 (72h) | 9.6 |
All acute and chronic freshwater test results are > 1 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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