Registration Dossier
Registration Dossier
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EC number: 606-833-1 | CAS number: 21800-83-9
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Referenceopen allclose all
- Reference Type:
- other: predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- QSAR Toolbox 3.1.0.21
- Reference Type:
- other: predicted data
- Title:
- No information
- Author:
- Gedeon Richter Plc. Health and Safety Department
- Year:
- 2 015
- Bibliographic source:
- T.E.S.T. version 4.1
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July2008
Test material
- Reference substance name:
- (+)-13-Ethylgon-4-ene-3,17-dione
- EC Number:
- 606-833-1
- Cas Number:
- 21800-83-9
- Molecular formula:
- C19H26O2
- IUPAC Name:
- (+)-13-Ethylgon-4-ene-3,17-dione
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 3.524 mg/L
- Nominal / measured:
- estimated
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Software Database / Method Endpoint Test duration Species Predicted value QSAR Toolbox Aquatic Japan MoE LC50 96 h Oryzias latipes 10 mg/L T.E.S.T. Group Contribution Method LC50 96 h Fathead minnow 1,08 mg/L T.E.S.T. FDA Method LC50 96 h Fathead minnow 3,81 mg/L T.E.S.T. Nearest neighbor method LC50 96 h Fathead minnow 1,53 mg/L T.E.S.T. Consensus method LC50 95 h Fathead minnow 1,2 mg/L Inferential result 3,524 mg/L
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- According to (Q)SAR modells: QSAR Toolbox, T.E.S.T. the predicted values indicated that levodione is hazardous to fishes. The result meets the requirement of Aquatic Acute Category 2.
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