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EC number: 239-854-6
CAS number: 15763-76-5
The sensitization potential of sodium cumene sulfonate was assessed in a
study where one group of 20 test animals was treated with 0.4 ml of
undiluted sodium cumene sulphonate for an exposure period of once weekly
to 6 hours induction exposures for 3 weeks. After a 2 week rest period,
both test (20) and control (10) animals were challenged with 0.4 ml of
undiluted sodium cumene sulphonate.
On challenge with 0.4 ml of undiluted sodium cumene sulphonate, no
reaction was observed in any of the test animals and conrtrol animals at
both the 21 -hour and 45 -hour reading. No evidence for sensitization
was observed in this study.
There are a total of 4 skin sensitization studies on the hydrotrope
All studies gave negative responses for sensitization.
The in vivo study data were obtained in studies performed before any in
vitro sensitization tests tests had been validated and accepted for
There are 4 skin sensitisation studies for the hydrotrope category
substances. The 4 studies consistently support a conclusion that these
substances are "not sensitising".
The available studies demonstrate that the hydrotrope category
substances are not skin sensitizers. Therefore a classification is not
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