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EC number: 239-854-6
CAS number: 15763-76-5
Short-term toxicity data for each type of organism indicate the Hydrotropes are of low toxicity to aquatic organisms. The two available fish studies for sodium xylenesulphonate and calcium xylenesulphonate report similar acute toxicity values of > 1,000 and 1,580 mg/L. Short-term data for aquatic invertebrates ranged from 40.3 to > 1,020 mg/L corresponding to four Hydrotrope category substances. Toxicity was not observed in the studies where the results are reported as “>” or “=>” and it is concluded that toxicity to aquatic invertebrates is >1,000 mg/L (key study). Short-term toxicity to algae was reported in three studies corresponding to three different Hydrotrope category substances. The EC50 based on growth rates ranged from 150 mg/L to 758 mg/L. The consistent trend is for low toxicity to algae across the Hydrotrope category.
Two activated sludge respiration inhibition studies were available for sodium toluenesulphonate and sodium cumenesulphonate. Both reported no toxicity at the limit test concentration, which was 1,000 mg/L for both substances. These studies indicate Hydrotropes are of comparable and low toxicities to microorganisms involved in sewage treatment processes.
From the available short-term toxicity data it can be concluded that aquatic organisms are of low sensitivity to Hydrotrope category substances. Most studies across the three trophic levels report no toxicity at the highest concentration tested. The Hydrotrope category substance with the lowest toxicity values for invertebrates and algae appears to be sodium toluenesulphonate. In addition, the studies relating to microbial activity (respiration) indicate low potential for toxicity at similar concentrations to fish, invertebrates and algae. As a combined body of evidence the toxicity data for these test substances can be considered to be representative of the Hydrotropes category. Long-term toxicity data are not required based on the low acute toxicity and ready biodegradability of the Hydrotropes. The reliable aquatic toxicity data are used in PNEC development across the category in accordance with guidance set out in Chapter R.6 (ECHA, 2008).
The EC/LC50 values are above 100 mg/L and the substances of the hydrotrope category have been shown to be readily biodegradable. Therefore a classification for environmental effects is not required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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