Triphenyl phosphate

Toxicity to microorganisms

Link to relevant study record(s)

Reference

Endpoint:

toxicity to microorganisms, other

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Conclusion from guideline study on biodegradability (also assessed by OECD)

Qualifier:

equivalent or similar to guideline

Guideline:

other: see below

Deviations:

not applicable

Principles of method if other than guideline:

OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))

GLP compliance:

no

Analytical monitoring:

no

Test organisms (species):

activated sludge

Test type:

static

Hardness:

Not applicable

Test temperature:

25 °C

pH:

Not applicable

Dissolved oxygen:

Not applicable

Salinity:

Not applicable

Nominal and measured concentrations:

100 mg/L

Details on test conditions:

Activated sludge study

Reference substance (positive control):

no

Duration:

28 d

Effect conc.:

100 mg/L

Remarks on result:

not measured/tested

Details on results:

BOD gave percentage degradation of 83, 94 and 92%

Since the biodegradability of TPP showed a result of 83  - 94 % after 28 d of
incubation with 30 mg/L sludge and 100 mg/L TPP in a test on ready  
biodegradability, there is no significant effect of TPP in the low  
concentration range expected.

Conclusions:

Under the conditions used TPP did not adversely affect the micro-organisms present

Executive summary:

The test was conducted in accordance to "301C, Ready Biodegradability: Modified MITI Test (I)" stipulated in the OECD Guidelines for Testing of Chemicals (1981).

TPP (100 mg/L) was incubated for 28 days at 25 °C with activated sludge (30 mg/L as concentration of suspended solid) in a volume of 300 mL. Degradation was determined by BOD. Under the conditions used TPP did not adversely affect the micro-organisms present, since the biodegradability of TPP showed a result of 83 - 94 %.

Description of key information

TPP (100 mg/L) was incubated for 28 days at 25 °C with activated sludge (30 mg/L as concentration of suspended solid) in a volume of 300 mL. Degradation was determined by BOD. Under the conditions used TPP did not adversely affect the microorganisms present, since the biodegradability of TPP showed a result of 83 - 94 %.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:

100 mg/L

Additional information

The key values should be understood as > 100 mg/L as no effect was observed up to the highest test concentration of 100 mg/L.