Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-572-9
CAS number: 1332-65-6
A range of studies are available that relate to copper toxicity towards amphibians. Only nominal NOECs/EC50 values are available and these were therefore not used for the PNEC derivation.
Almost all tests gathered from literature on
the effect of copper towards amphibians were performed on early life
stages, in laboratory water (with lowDOCconcentration),
with 4 days exposure times and according to standard guidelines. The
results clearly show that amphibians (data were found for Xenopus
laevis, Rana pipiens, Rana ridibunda, Rana hexadactyla, Rana
Sphenocephala and Rana tigrina) are not sensitive towards
copper. Indeed LC50 and NOEC/(L(E) C10 values respectively between 39
and 1,250 µg/l and between 40 and 100,000 µg/l were found.
Most of the studies report however EC50
values and test concentrations were not measured and therefore the
data-reliability is low. These data were therefore not retained for the
Fort et al., 2000 determined optimal copper
concentration ranges for the early life stages of the amphibiaX.
Laevis: 1 to 10 µg Cu/L. Copper
deficiency was observed at copper concentrations < 1 µg Cu/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Esta web utiliza cookies para mejorar su experiencia de navegación en nuestros sitios web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again