Registration Dossier
Registration Dossier
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EC number: 203-377-1 | CAS number: 106-24-1
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable publication which meets basic scientific principles
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Absorption of ethereal oils and substances contained in them through the skin
- Author:
- Meyer F and Meyer E
- Year:
- 1 959
- Bibliographic source:
- Arzneimittel-Forschung, 9, 516-519.
- Reference Type:
- secondary source
- Title:
- Fragrance Raw Materials Monographs
- Author:
- Opdyke DLJ
- Year:
- 1 974
- Bibliographic source:
- Food and Cosmetics Toxicology, Vol. 12: 881-882
Materials and methods
- Principles of method if other than guideline:
- skin absorption study
Test material
- Reference substance name:
- Geraniol
- EC Number:
- 203-377-1
- EC Name:
- Geraniol
- Cas Number:
- 106-24-1
- Molecular formula:
- C10H18O
- IUPAC Name:
- 3,7-dimethylocta-2,6-dien-1-ol
Constituent 1
Test animals
- Species:
- mouse
- Sex:
- male
Administration / exposure
- Type of coverage:
- not specified
- Duration of exposure:
- 2 h
- No. of animals per group:
- total 230 mice
Results and discussion
Any other information on results incl. tables
No absorption was reported.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
