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EC number: 242-555-3 | CAS number: 18755-43-6
Endpoint summary
Administrative data
Description of key information
Additional information
Based on the presented results dimethyl propylphosphonate has to be scored as not harmful towards aquatic organisms. Data on aquatic effects of dimethyl propylphosphonate are available on three trophic levels (fish, daphnia and algae) for acute toxicity.
In order to test the acute toxicity to fish, Brachydanio rerio was exposed to the test solution of one nominal concentration of dimethyl propylphosphonate (100 mg/L) and blank control solution for a period of 96 h under static conditions. The measured concentrations confirmed that deviation from the nominal concentrations were less than 20 % (measured concentrations were in the range of 94.0 - 104.9 % of nominal concentrations). No toxic effect and abnormal behavior were observed. This toxicity study meets the requirements of the guideline for the acute fish studies.
A LC0 ≥ 99.1 mg/L (arithmetic mean of the analytically determined test concentrations) was determined.
Concerning the toxicity towards aquatic invertebrates, an acute toxicity test to Daphnia magna was performed according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test). No toxic effect and abnormal behavior were observed during 48 h of exposure. As analytical monitoring was performed showing stability of dimethyl propylphosphonate, the results of EC50 > 90 mg/L and EC0 >= 90 mg/L relate to measured initial concentrations.
In a toxicity test towards algae, the fresh water alga Desmodesmus subspicatus was exposed to dimethyl propylphosphonate for 72 h. The experiment was conducted according to OECD Guideline 201 (Alga, Growth Inhibition Test). An EC50 > 88.4 mg/L and a NOEC >= 88.4 mg/L, based on measured initial concentrations was obtained in this test. Analytical monitoring was carried out and stability of dimethyl propylphosphonate was confirmed during the duration of exposure.
In order to test the toxicity of dimethyl propylphosphonate to microorganisms, activated sludge from a laboratory sewage treatment plant was exposed to the test solution of three nominal concentrations of dimethyl propylphosphonate (100, 1000 and 10000 mg/L), blank control solution and solution with positive reference substance for a period of 3 h. Dissolved oxygen was recorded and respiration rates were calculated. No physicochemical oxygen consumption was observed at the highest concentration of dimethyl propylphosphonate. No respiration inhibition was observed at 100 and 1000 mg/L; and only 9.5 % inhibition at 10000 mg/L. This toxicity study meets the requirements of the guideline for the acute microorganism studies.
An EC50 >10000 mg/L was determined in this test.
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