Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 813-618-8 | CAS number: 1269400-04-5
Guidance on Safe Use
Administrative data
First-aid measures
Description of First Aid Measures
Eye Contact: Flush with water while holding eyelids open for at least 15 minutes. Seek medical attention immediately.
Skin Contact: Remove contaminated clothing. Flush area with large amounts of water. Use soap. Seek medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Wash out mouth with water. Do not induce vomiting unless directed by medical personnel. Seek medical attention immediately.
Inhalation: Remove to fresh air and keep patient at rest. Seek medical attention immediately.
Symptoms and Effects of Exposure: No data available
Medical Conditions Aggravated by Exposure: None known
Indication of the Immediate Medical Attention and Special Treatment Needed
Notes to Physician: None
Fire-fighting measures
Extinguishing Media: Extinguish fires with CO2, extinguishing powder, foam, or water.
Special Hazards Arising from the Substance or Mixture
Hazardous Combustion Products: Formation of toxic gases is possible during heating or fire. May include oxides of carbon and nitrogen.
Fire / Explosion Hazards: Very strong dust explosion characteristic. Very high sensitivity of a dust cloud to ignition, based on minimum ignition energy.
Advice for Fire-FightersL During all firefighting activities, wear appropriate protective equipment, including self-contained breathing apparatus.
Accidental release measures
Personal Precautions, Protective Equipment and Emergency Procedures
Personnel involved in clean-up should wear appropriate personal protective equipment (see Section 8). Minimize exposure.
Environmental Precautions: Place waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental release.
Methods and Material for Containment and Cleaning Up
Avoid use of a filtered vacuum to clean spills of dry solids, due to the potential for electrostatic discharge and the very strong dust explosion characteristic and very high sensitivity to ignition.
Additional Consideration for Large Spills: Non-essential personnel should be evacuated from affected area. Report emergency situations immediately. Cleanup operations should only be undertaken by trained personnel.
Handling and storage
Precautions for Safe Handling:
All conductive elements of the system that contact the dry substance should be properly bonded and grounded and equipped
with proper explosion relief or suppression systems. This material should not be flowed through nonconductive ducts or pipes
because of the potential for electrostatic discharge ignition. Restricting the use of high resistivity materials, such as plastics,
should be considered. Avoid open handling. Minimize dust generation. Use local exhaust ventilation or perform work under fume
hood/fume cupboard. Avoid inhalation and contact with skin, eye, and clothing. When handling, use appropriate personal
protective equipment (see Section 8). Wash hands and any exposed skin after removal of PPE. Releases to the environment
should be avoided. Review and implement appropriate technical and procedural waste water and waste disposal measures to
prevent occupational exposure or environmental releases. Potential points of process emissions of this material to the
atmosphere should be controlled with dust collectors, HEPA filtration systems or other equivalent controls.
Conditions for Safe Storage, Including any Incompatibilities:
Store at room temperature in properly labeled containers. Keep away from heat, sparks and flames.
Specific end use(s): Pharmaceutical process intermediate
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 2811
Shippingopen allclose all
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- UN 2811
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- UN 2811
Shippingopen allclose all
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN 2811
Shippingopen allclose all
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Control Parameters
The purpose of the Occupational Exposure Band (OEB) classification system is to separate substances into different Hazard categories when the available data are sufficient to do so, but inadequate to establish an Occupational Exposure Limit (OEL). The OEB given is based upon an analysis of all currently available data; as such, this value may be subject to revision when new information becomes available.
Pfizer Occupational Exposure Band (OEB): OEB 3 (control exposure to the range of 10ug/m3 to < 100ug/m3)
Exposure Controls
Engineering controls should be used as the primary means to control exposures. Use process containment, local exhaust ventilation, or other engineering controls to maintain airborne levels within the OEB range.
Personal Protective Equipment: Refer to applicable national standards and regulations in the selection and use of personal protective equipment (PPE). Contact your safety and health professional or safety equipment supplier for assistance in selecting the correct protective clothing/equipment based on an assessment of the workplace conditions, other chemicals used or present in the workplace and specific operational processes.
Hands:Wear impervious gloves (e.g. Nitrile, etc.) as minimum protection. (Protective gloves must meet the standards in accordance with EN374, ASTM F1001 or international equivalent.)
Eyes: Wear safety glasses as minimum protection. (Safety glasses must meet the standards in accordance with EN166, ANSI Z87.1 or international equivalent.)
Skin:Wear impervious protective clothing when handling this compound. (Protective clothing must meet the standards in accordance with EN13982, ANSI 103 or international equivalent.)
Respiratory protection: Under normal conditions of use, if the applicable Occupational Exposure Band (OEB) is exceeded, wear an appropriate respirator with a protection factor sufficient to control exposures to below the OEB (e.g. particulate respirator with a half mask, P3 filter). (Respirators must meet the standards in accordance with EN140, EN143, ASTM F2704-10 or international equivalent.)
Stability and reactivity
Reactivity: No data available
Chemical Stability: Stable under normal conditions of use.
Possibility of Hazardous Reactions
Oxidizing Properties: No data available
Conditions to Avoid: Fine particles (such as dust and mists) may fuel fires/explosions. Keep away from heat and other sources of ignition, including electrostatic discharge.
Incompatible Materials: As a precautionary measure, keep away from strong oxidizers
Hazardous Decomposition Products: No data available
Disposal considerations
Waste Treatment Methods:
Dispose of waste in accordance with all applicable laws and regulations. Member State specific and Community specific provisions must be considered. Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure and environmental release. It is recommended that waste minimization
be practiced. The best available technology should be utilized to prevent environmental releases. This may include destructive techniques for waste and wastewater.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
