Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
202-859-9
CAS no.:
100-51-6
Index number:
Molecular formula:
C7H8O
SMILES:
OCC1=CC=CC=C1
InChI:
InChI=1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
15
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is harmful if swallowed and is harmful if inhaled.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes serious eye irritation.

Breakdown of all 4705 C&L notifications submitted to ECHA

Acute Tox. 4 H302 Harmonised Classification
Acute Tox. 4 H332 Harmonised Classification
Eye Irrit. 2 H319
Acute Tox. 4 H312
Eye Dam. 1 H318
Skin Irrit. 2 H315
Skin Sens. 1 H317
Eye Irrit. 2A H319
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 33 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about this substance from registration dossiers.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is being reviewed for use as a biocide in the EEA and/or Switzerland, for: product preservation.

This substance is used in the following products: washing & cleaning products, coating products, adhesives and sealants and inks and toners.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, closed batch processing in synthesis or formulation, transfer of chemicals at dedicated facilities, treatment of articles by dipping and pouring and laboratory work.

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and paper used for articles with intense direct dermal (skin) contact during normal use such as personal hygiene articles (e.g. nappies, feminine hygiene products, adult incontinence products, tissues, towels, toilet paper).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: building & construction work, health services and scientific research and development. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, non-industrial spraying, treatment of articles by dipping and pouring, roller or brushing applications and transfer of substance into small containers.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: polymers, coating products and adhesives and sealants.

This substance is used in the following areas: building & construction work. This substance is used for the manufacture of: chemicals, textile, leather or fur, pulp, paper and paper products, rubber products and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, treatment of articles by dipping and pouring, transfer of substance into small containers, roller or brushing applications, mixing in open batch processes, industrial spraying and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • AKZO Nobel Car Refinishes B.V., Rijksstraatweg 31 2170 BA Sassenheim Netherlands
  • B-Lands Consulting (811708-9), OR of Hubei Greenhome Materials Technology, Inc. 5 Place Robert Schuman - BP 1516 38025 Grenoble France
  • B-Lands Consulting (811735-3), BP 1516 5 Place Robert Schuman 38025 Grenoble France France
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • C.S.B. GmbH, Duesseldorfer Str.113 47809 Krefeld Germany
  • Cardolite Specialty Chemicals Europe NV (OR for IXE), Wijmenstraat 21 K bus 2 B-9030 Mariakerke (Gent) Belgium
  • Chemical Inspection & Regulation Service Limited, CIRS, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Liaocheng Luxi Benzyl Chloride Chemical CO.,Ltd.), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Colorants Solutions Deutschland GmbH, Brüningstrasse 50 65929 Frankfurt am Main Germany
  • Croda EU B.V. (OR1), Buurtje 1 2802 BE Gouda Netherlands
  • D.M.CHEMICALS LTD, Westbrook Road Kingsley WA6 8EA Frodsham Cheshire United Kingdom
  • Emerald Kalama Chemical, B.V., Montrealweg 15 3197 KH ROTTERDAM BOTLEK Netherlands
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Intertek Deutschland GmbH 04, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • JT International Germany GmbH - FF, Diedenhofener Strasse 20-30 54294 Trier Germany
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • NWL FRANCE SERVICES, 122 avenue du Général Leclerc 92100 Boulogne Billancourt France France
  • Penman Consulting bvba 09, Avenue des Arts 10 B-1210 Brussels Belgium
  • PILOT CORPORATION OF EUROPE, PAE de la Caille 74350 ALLONZIER LA CAILLE France
  • Prakash Chemicals Europe B.V., Lotte Stam Beestr 136, 3066HB Rotterdam Netherlands Netherlands
  • PRODUCTOS CAPILARES L'OREAL S.A., Calle Lopez Bravo n°78 Poligono Industrial Villalonquéjar 09001 BURGOS Spain
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACHLaw Ltd (acting as OR for KLJ Organic Limited), Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • Sigma-Aldrich Ireland Ltd, Vale Road . Arklow Co. Wicklow Ireland
  • Solenis Netherlands B.V., Fascinatio Boulevard 522 2909 VA CAPELLE A/D IJSSEL Netherlands
  • Stewardship Chemicals 33, Green Lowe Farm, Shawclough Road Waterfoot BB4 9SA Rossendale Lancashire United Kingdom
  • StonCor Europe, Rue du Travail, 9 1400 Nivelles Belgium
  • UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
  • Valtris AO Maastricht BV, Ankerkade, 111 6222 NL Maastricht Netherlands
  • Vantage Specialty Chemicals, 19 avenue des Fjords 91140 VILLEBON-SUR-YVETTE France
  • Arcerion GmbH, Gabrielenstr. 15 80636 München Germany

Substance names and other identifiers

Benzyl alcohol
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Biocidal active substances, REACH pre-registration, Other, Cosmetic Products Regulation, Annex III - Restricted Substances, Cosmetic Products Regulation, Annex V - Allowed Preservatives, Annex II, Sec III - Allergenic Fragrances Banned/Restricted in Toys, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
alcohol bencílico (es)
C&L Inventory
alcool benzilico (it)
C&L Inventory
alcool benzylique (fr)
C&L Inventory
alkohol benzylowy (pl)
C&L Inventory
Bensüülalkohol (et)
C&L Inventory
Bentsyyli-alkoholi (fi)
C&L Inventory
benzil alcool (ro)
C&L Inventory
benzil alkohol (sl)
C&L Inventory
benzil-alkohol (hu)
C&L Inventory
benzilo alkoholis (lt)
C&L Inventory
benzilspirts (lv)
C&L Inventory
benzylalcohol (nl)
C&L Inventory
benzylalkohol (cs)
C&L Inventory
fenylokarbinol (pl)
C&L Inventory
fenylometanol (pl)
C&L Inventory
álcool benzílico (pt)
C&L Inventory
βενζυλική αλκοόλ (el)
C&L Inventory
бензилов алкохол (bg)
C&L Inventory
Benzenemethanol
Other
Alcool, benzylique
C&L Inventory
Benzenemethanol, Phenylcarbinol
Registration dossier
Benzyl alcohol, Phenylmethanol
C&L Inventory
benzyl alcohol; benzenemethanol; phenylmethanol ...
C&L Inventory
benzyl alkohol
C&L Inventory
Benzylic alcohol
C&L Inventory
Bezyl alcohol
C&L Inventory
fenilmetanol
C&L Inventory
fenylmethanol
C&L Inventory
hydroxymethylobenzene
C&L Inventory
Phenyl methanol
C&L Inventory
phenyl-methanol
C&L Inventory
Phenylcarbinol
C&L Inventory
PHENYLMETHANOL
C&L Inventory, Registration dossier, Other
Phenylmethyl alcohol
C&L Inventory
Phenylmethylalcohol
C&L Inventory
(Hydroxymethyl)benzene
Registration dossier
.alpha.-Hydroxytoluene
Registration dossier
.alpha.-Toluenol
Registration dossier
ALPHA-HYDROXYTOLUOL
Registration dossier
ALPHA-OXYTOLUOL
Registration dossier
Benzenecarbinol
Registration dossier
Benzenemethanol (9CI)
Registration dossier
BENZOLCARBINOL
Registration dossier
BENZOLMETHANOL
Registration dossier
Benzyl alcohol (8CI)
Registration dossier
HYDROXYMETHYLBENZOL
Registration dossier
PHENYLMETHYLALKOHOL
Registration dossier
Sunmorl BK 20
Registration dossier
Üveglakk 1:1 B komponens
C&L Inventory
100-51-6
CAS number
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Biocidal active substances, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex III - Restricted Substances, Cosmetic Products Regulation, Annex V - Allowed Preservatives, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Annex II, Sec III - Allergenic Fragrances Banned/Restricted in Toys, Waste Framework Directive, Annex III - Waste - Hazardous Properties
1336-27-2
CAS number
Other
185532-71-2
CAS number
Other
603-057-00-5
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 6 studies submitted
  • 3 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [3]
C Form
Liquid (67%), Other (33%) [3]
C Odour
Other (100%) [3]
C Substance type
Organic (100%) [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 2 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 8 studies submitted
  • 3 studies processed
R Melting / freezing point
-15.4 - -15.2 °C [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-15.4 °C

Boiling point

Study results
  • 10 studies submitted
  • 3 studies processed
R Boiling point
205.3 - 205.31 °C @ 101.3 - 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 2 1
Supporting study 2
Weight of evidence
Other 1 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
205.3 °C

Density

Study results
  • 6 studies submitted
  • 4 studies processed
R Density
1.02 - 1.06 g/cm³ @ 0 - 60 °C [7]
R Relative density
1.04 @ 24 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence 3
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.045

Vapour pressure

Study results
  • 11 studies submitted
  • 3 studies processed
R Vapour pressure
7 - 63 Pa @ 20 - 45 °C [15]

Type of Study provided
Studies with data
Key study 3
Supporting study 1 2
Weight of evidence
Other 5
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
7 Pa @ 20 °C

Partition coefficient

Study results
  • 11 studies submitted
  • 3 studies processed
R Log Pow
0.87 - 1.1 @ 20 - 25 °C [16]

Type of Study provided
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other 4 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
1.05 @ 20 °C

Water solubility

Study results
  • 11 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2 1
Supporting study 4
Weight of evidence
Other 1 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
40 g/L @ 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
39 mN/m

Flash point

Study results
  • 6 studies submitted
  • 3 studies processed
R Flash point
100.4 °C [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
100.4 °C

Auto flammability

Study results
  • 5 studies submitted
  • 3 studies processed
R Autoflammability / self-ignition
436 °C [3]

Type of Study provided
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
436 °C

Flammability

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other 2
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 3 studies submitted
  • 3 studies processed
C Dissociating properties
No (100%) [3]
R Dissociation constant
15.4 @ 25 °C [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
15.4

Viscosity

Study results
  • 4 studies submitted
  • 4 studies processed
R dynamic viscosity (in mPa s)
5.05 - 5.584 [4]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
5.84 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 4 studies submitted
  • 2 studies processed
R Degradation rate constant (OH radicals)
0 cm³ molecule-1 d-1 [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 21 studies submitted
  • 4 studies processed
C Interpretation of results
Readily biodegradable (100%) [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 4 2
Weight of evidence
Other 6 5
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
1.37 L/kg ww

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 3 studies submitted
  • 2 studies processed
R Koc
13.25 - 21.46 L/kg [4]
R log Koc
1.122 - 1.332 L/kg [4]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
15.7

Henrys law constant (H)

Study results
  • 3 studies submitted
  • 2 studies processed
R H - (pressure) m³/mol
0.005 Pa m³/mol @ 25 °C and 101.325 kPa [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0.088 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Study results
  • 2 studies submitted
  • 2 studies processed
% Distribution in Media:
R Air 1.03 % [2]
R Water 34 % [2]
R Soil 64.8 % [2]
R Sediment 0.093 % [2]
R Suspended sediment 0 % [2]
R Biota 0 % [2]
R Aerosol 0 % [2]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 3 summaries submitted
  • 3 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 1 - 1.02 mg/L (3)
Intermittent releases (freshwater) 2.3 mg/L (3)
Marine water 100 - 102 µg/L (3)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 39 mg/L (3)
Sediment (freshwater) 5.27 mg/kg sediment dw (1)
Sediment (marine water) 527 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (3)
Hazard for Terrestrial Organism
Soil 456 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (3)

Short–term toxicity to fish

Study results
  • 13 studies submitted
  • 3 studies processed
P/RResults
LC50 (4 days) 460 mg/L [3]
LC50 (72 h) 460 mg/L [3]
LC50 (48 h) 770 mg/L [3]
LC50 (24 h) 770 mg/L [3]
LC50 (60 min) 770 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 3 2
Weight of evidence
Other 2 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
460 mg/L

Long–term toxicity to fish

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
NOEC (30 days) 48.897 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 9 studies submitted
  • 5 studies processed
P/RResults
EC50 (48 h) 230 mg/L [3]
LC50 (48 h) 260.415 mg/L [2]

Type of Study provided
Studies with data
Key study 3 2
Supporting study 2
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
230 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 3 studies processed
P/RResults
NOEC (21 days) 51 - 66 mg/L [5]
EC50 (21 days) 66 mg/L [1]

Type of Study provided
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
51 mg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 9 studies submitted
  • 5 studies processed
P/RResults
EC50 (4 days) 76.828 mg/L [2]
EC50 (72 h) 500 - 770 mg/L [6]
NOEC (30 days) 23.486 mg/L [2]
NOEC (72 h) 310 mg/L [6]

Type of Study provided
Studies with data
Key study 3 2
Supporting study 2
Weight of evidence
Other 1 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
770 mg/L
EC10 or NOEC for freshwater algae
310 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 11 studies submitted
  • 3 studies processed
P/RResults
IC50 (49 h) 2.1 g/L [3]
IC50 (24 h) 390 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 3 2
Weight of evidence
Other 1 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
390 mg/L

Sediment toxicity

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 3
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 3
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 3
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 3
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 22 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 110 mg/m³ acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 40 mg/kg bw/day repeated dose toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 5.4 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 27 mg/m³ acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 20 mg/kg bw/day acute toxicity
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 20 mg/kg bw/day acute toxicity
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2
Supporting study 1
Weight of evidence 2 2
Other 1
Data waiving
no waivers
Study data: dermal absorption
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence 1
Other 1 1
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 10 studies submitted
  • 3 studies processed
P/RResults
LD50 1.55 mL/kg bw (rat) [1]
LD50 1 580 mg/kg bw (mouse) [2]
M/CInterpretations of results
Category 4 based on GHS criteria [2]

Type of Study provided
oral
Studies with data
Key study 3
Supporting study
Weight of evidence
Other 6 1
Data waiving
no waivers
inhalation
  • 7 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 4.178 mg/L air (rat) [1]

inhalation
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 3
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
dermal
  • 7 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Other [2]

dermal
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 2
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
other routes
  • 12 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other 6 6
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 1 620 mg/kg bw
Inhalation route:
No adverse effect observed Discriminating conc. 4 178 mg/m³

Irritation / corrosion

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other 4 1
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 4
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)
Respiratory
No adverse effect observed (not irritating)

Sensitisation

Study results
Study data: skin
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 8
Other 1 1
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 20 studies submitted
  • 13 studies processed
P/RResults
NOAEL (rat): 400 - 500 mg/kg bw/day [7]
NOAEL (mouse): 200 - 250 mg/kg bw/day [6]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 3
Weight of evidence 12
Other 4
Data waiving
no waivers
Study data: inhalation
  • 6 studies submitted
  • 3 studies processed
P/RResults
NOAEC (rat): 1.072 - 1.29 mg/L air [3]

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence 2
Other 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 3
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 400 mg/kg bw/day (chronic, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 072 mg/m³ (subacute, rat)
Inhalation route - local effects:
Adverse effect observed NOAEC 1 072 mg/m³ (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 23 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2
Supporting study
Weight of evidence 9 2
Other 10
Data waiving
no waivers
Study data: in vivo
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 2
Weight of evidence 5
Other 2
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence 2
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 22 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 4
Supporting study 3 2
Weight of evidence 4 2 4 1
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: developmental
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study 2 6
Weight of evidence 4 3
Other 2
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant