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Registry of restriction intentions until outcome

The registry of restriction intentions until outcome lists the intentions and Annex XV restriction proposals received by ECHA.

A restriction proposal may be prepared by a Member State or by ECHA at the request of the Commission or on its own initiative for substances in the Authorisation List. It is a legal requirement for a Member State to notify ECHA of its intention to prepare a restriction dossier. The advance notice enables interested parties to plan and prepare for commenting later on.

Interested parties can follow the progress of a proposal through the restriction process, from the notification of the intention to the adoption of the final opinions by the Committee for Risk Assessment (RAC) and the Committee for Socio-economic Analysis (SEAC), and the adoption of the restriction by the European Commission.

Stakeholders are encouraged to submit any relevant information to the dossier submitters during the preparation of the restriction proposal and during the consultations. Information to motivate any exemptions to the scope described in the intention is particularly useful to receive in the preparatory phase of the dossier.

4-Nonylphenol, branched and linear and 4-Nonylphenol, branched and linear, ethoxylated

EC / List no: - CAS no: -
CLP Annex VI Index number
Further substance information
Details on the scope of restriction
Placing on the market of textile and leather articles containing NP and NPE
Reason for restriction
NP and NPEs have been found in environmental samples taken from freshwater, saltwater, groundwater, sediment, soil and aquatic biota. NP has also been detected in human breast milk, blood, and urine and is associated with reproductive and developmental effects in rodents. NP is persistent in the aquatic environment, moderately bioaccumulative, and extremely toxic to aquatic organisms. NP has also been shown to exhibit estrogenic properties in vitro and in vivo assays. NP’s main use is in the manufacture of NPEs.
NPEs are nonionic surfactants that have been used in a wide variety of industrial applications and consumer products. They can be found in textile (and leather?) articles. NPEs, though less toxic and persistent than NP, are also highly toxic to aquatic organisms, and, in the environment, degrade into NP.
Levels of NP in waters above the environmental quality standards in the Water Framework Directive (WFD) is found in several waters despite the strict restriction on the use of Nonylphenol (NP) and Nonylphenoletoxilates (NPEO) under the limitations directive 76/769/EEC (now in Reach Annex XVII, entry 46) having been in force since January 2005. NP and NPEO in textiles have been identified as a significant source of NP in the environment.
The Swedish Chemicals Agency is therefore investigating the possibility to propose a restriction on the placing of the market of textile and leather articles containing NP or NPEO.
Not conforming
Date of intention
Expected date of submission
Withdrawal date
Reason for withdrawal
The restriction dossier does not conform to the requirements of Annex XV dossier.
Start of Call for Evidence consultation
Deadline for comments on the Call for Evidence
Start of second Call for Evidence consultation
Deadline for comments on the second Call for Evidence
Start of third Call for Evidence consultation
Deadline for comments on the third Call for Evidence
Restriction report (and annexes)
Information note on restriction report
Start of Annex XV report consultation
1st deadline for comments on Annex XV report
Final deadline for comments on Annex XV report
Comments on Annex XV report
Opinion of RAC (and minority positions)
Draft opinion of SEAC
RAC & SEAC (draft) Background document (and annexes)
Start of SEAC draft opinion consultation
Deadline for comments on SEAC draft opinion
Comments on SEAC draft opinion
Compiled RAC and SEAC opinion (and minority positions)
Final background document (and annexes)
Adopted restriction/Commission communication
Latest update

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Group members
This group of substance has the following member substances:
Name EC / List no. CAS no. Association
2-[2-(4-nonylphenoxy)ethoxy]ethanol 243-816-4 20427-84-3 Expert judgement
2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol 230-770-5 7311-27-5 Expert judgement
2-{2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethoxy}ethanol 687-833-9 1119449-38-5 Expert judgement
4-t-Nonylphenol-diethoxylate - 156609-10-8 Expert judgement
3,6,9,12-Tetraoxatetradecan-1-ol, 14-(4-nonylphenoxy)- - 20636-48-0 Expert judgement
Poly(oxy-1,2-ethanediyl), alpha-(2-nonylphenyl)-omega-hydroxy- - 51938-25-1 Expert judgement
Ethanol, 2-(2-(2-(nonylphenoxy)ethoxy)ethoxy)- - 27176-95-0 Expert judgement
Tetraoxyethylene nonylphenyl ether - 27176-97-2 Expert judgement
3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-(nonylphenoxy)- - 27177-01-1 Expert judgement
Ethanol, 2-(2-(2-(4-nonylphenoxy)ethoxy)ethoxy)- - 51437-95-7 Expert judgement
Nonylphenylpolyoxyethylene sulfosuccinate - 54612-36-1 Expert judgement
3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol, 29-(isononylphenoxy)- - 65455-72-3 Expert judgement
Ethanol, 2-(4-nonylphenoxy)- - 104-35-8 Expert judgement
2-(isononylphenoxy)ethanol 284-987-5 85005-55-6 Expert judgement
3,6,9,12-Tetraoxatetradecan-1-ol, 14-(4-nonylphenoxy)-, branched 293-926-1 91648-64-5 Expert judgement
Ethanol, 2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]-, branched 294-139-6 91673-24-4 Expert judgement
4-Nonylphenol, ethoxylated
1 - 2.5 moles ethoxylated
500-045-0 26027-38-3 Expert judgement
Nonylphenol, branched, ethoxylated
1 - 2.5 moles ethoxylated
500-209-1 68412-54-4 Expert judgement
4-Nonylphenol, branched, ethoxylated
1 - 2.5 moles ethoxylated
500-315-8 127087-87-0 Expert judgement
Poly(oxy-1,2-ethanediyl), alpha-sulfo-omega-(nonylphenoxy)-, ammonium salt (1:1) 618-573-6 9051-57-4 Expert judgement
26-(4-nonylphenoxy)-3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol 604-395-6 14409-72-4 Expert judgement
Poly(oxy-1,2-ethanediyl), alpha-sulfo-omega-(nonylphenoxy)-, branched, ammonium salt 614-698-5 68649-55-8 Expert judgement
Nonylphenol, branched, ethoxylated, phosphated 614-460-0 68412-53-3 Expert judgement
Poly(oxy-1,2-ethanediyl), alpha-sulfo-omega-(nonylphenoxy)-, sodium salt (1:1) 618-487-9 9014-90-8 Expert judgement
p-Nonylphenol hexaethoxylate - 34166-38-6 Expert judgement
2-(2-nonylphenoxy)ethanol; phosphoric acid 610-741-7 51811-79-1 Expert judgement
Ethyl perfluorooctanoate 221-468-4 3108-24-5 Expert judgement
14-(nonylphenoxy)-3,6,9,12-tetraoxatetradecan-1-ol 247-555-7 26264-02-8 Expert judgement
26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol 247-816-5 26571-11-9 Expert judgement
2-[2-(nonylphenoxy)ethoxy]ethanol 248-291-5 27176-93-8 Expert judgement
20-(nonylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol 248-292-0 27177-03-3 Expert judgement
23-(nonylphenoxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-ol 248-293-6 27177-05-5 Expert judgement
20-(4-nonylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol 248-743-1 27942-27-4 Expert judgement
2-(nonylphenoxy)ethanol 248-762-5 27986-36-3 Expert judgement
20-(isononylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol 265-785-6 65455-69-8 Expert judgement
2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethanol 687-832-3 1119449-37-4 Expert judgement

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