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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: short-term
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Standard QSAR modeling software
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: QSAR
Title:
ECOSAR assessment
Author:
3V Sigma
Year:
2012
Bibliographic source:
ECOSAR assessment
Report Date:
2012

Materials and methods

Principles of method if other than guideline:
ECOSAR v1.11 Q(SAR) modeling system

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
other: Earthworm
Animal group:
annelids

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
> 2 070 mg/kg soil dw
Nominal / measured:
estimated
Conc. based on:
test mat.
Remarks on result:
other: ECOSAR
Details on results:
The substance shows no acute toxicity to earthworms at the limits of water solubility. ECOSAR v1.11 was used to estimate toxicity based on the ester class, which shows similar results as the neutral organic class used for the aquatic testing. No acute or chronic toxicity to aquatic organisms was predicted, as shown in the long-term toxicity endpoints for fish and aquatic invertebrates.

Based on the lack of toxicity and the expected lack of signficant exposure, no further testing is recommended.

Applicant's summary and conclusion

Conclusions:
The substance is not toxic to earthworms at the limits of water solubility.
Executive summary:

The substance shows no acute toxicity to earthworms at the limits of water solubility. ECOSAR v1.11 was used to estimate toxicity based on the ester class, which shows similar results as the neutral organic class used for the aquatic testing. No acute or chronic toxicity to aquatic organisms was predicted, as shown in the long-term toxicity endpoints for fish and aquatic invertebrates.

Based on the lack of toxicity and the expected lack of signficant exposure, no further testing is recommended.