Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1995
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995
Report Date:
1995

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
not specified
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Uvasorb HEB
- Molecular formula (if other than submission substance): C44H59N7O5
- Molecular weight (if other than submission substance): 765
- Physical state: solid
- Analytical purity: 98.3%
- Composition of test material, percentage of components: 2-ethylhexyl-p.aminobenzoate (0.3%) water (0.25%)

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
4.12
Temp.:
20 °C
pH:
6.2

Any other information on results incl. tables

Test no. P log Pow

1A 23110 4.36

1B 19610 4.29

2A 9448 3.97

2B 8011 3.90

3A 12241 4.09

3B 12662 4.10

From the values elaboration a mean value of log Pow 4.12 with a standard deviation of 0.20 is obtained.

The pH of the aqueous phase was identical as distilled water used in the tests.

Applicant's summary and conclusion

Conclusions:
From the values elaboration a mean value of log Pow 4.12 with a standard deviation of 0.20 is obtained.