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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 11, 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution
Key result
Percentile:
D10
Mean:
ca. 143 µm
Remarks on result:
other: St. dev. not determined
Key result
Percentile:
D50
Mean:
ca. 351 µm
Remarks on result:
other: St. dev. not determined.
Key result
Percentile:
D90
Mean:
ca. 943 µm
Remarks on result:
other: St. dev. not determined.

The test item consisted of particles which appeared irregularly shaped.

The test item was tested as a liquid dispersion in demineralized water (with 1 % detergent). This homogenised dispersion was fed to the sample unit. Subsequently the diluted dispersion was pumped to the optical system. After passing the spectrometer the sample was pumped back into the small volume sample dispersion unit.

After adjusting the laser, measuring the background (demineralized water with 1 % detergent) and adjusting the correct particle concentration (obscuration) the measurement was started. The control software automatically performed three measurements. The average of these three measurements was given as result. Two test series of three measurements each were performed. The measurement time was12s.

The particle size distributions determined in the first and second test series are shown in Figure 1 (page 8) and Figure 2 (page 9), respectively. For each test series fractions (left axis of the ordinate) and the siftings (right axis of the ordinate) are presented in percent by volume as a function of the particle size. Median values were calculated from unrounded values.

 

The median particle size L50(D (v, 0.5): 50 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1st test series: L50 = 325.7 μm

2nd test series: L50 = 375.9 μm

The average of the median particle size L50 was: L50 = 351 μm

 

The particle size L10 (D (v, 0.1 ): 10 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1st test series: L10 = 113.8 μm

2nd test series: L10 = 172.2 μm

The average of the particle size L10 was: L10 = 143 μm

 

The particle size L90(D (v, 0.9): 90 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1st test series: L90 = 971.0 μm

2nd test series: L90 = 915.5 μm

The average of the particle size L90 was: L90 = 943 μm

 

The maximum was observed at approxmately 300 µm.

Conclusions:
The median particle size L50 of the test item deduced from the particle size distributions was 351 µm.
Executive summary:

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110 by laser diffraction. The median particle size L50 of the test item deduced from the particle size distributions was 351 µm.

Description of key information

The median particle size L50 of the test item deduced from the particle size distributions was 351 µm.

Additional information