Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 231-415-7 | CAS number: 7540-51-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption, other
- Remarks:
- in silico
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
Data source
Reference
- Reference Type:
- other: caculation
- Title:
- In Silico skin absorption model
- Author:
- Jie Shen, Lambros Kromidas, Terry Schultz, Sneha Bhatia
- Bibliographic source:
- An in silico skin absorption model for fragrance materials, Shen et al., 2014. Food and Chemical Toxicology 74 (2014) 164–176
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
Test material
- Reference substance name:
- (-)-3,7-dimethyloct-6-en-1-ol
- EC Number:
- 231-415-7
- EC Name:
- (-)-3,7-dimethyloct-6-en-1-ol
- Cas Number:
- 7540-51-4
- Molecular formula:
- C10H20O
- IUPAC Name:
- 3,7-dimethyloct-6-en-1-ol
Constituent 1
Results and discussion
Percutaneous absorption
- Parameter:
- other: Absorption based on calculated Jmax
- Absorption:
- <= 80 %
Any other information on results incl. tables
Calculated value Jmax = 45. 378
Absorption ≤ 80%
Applicant's summary and conclusion
- Conclusions:
- Calculated value Jmax = 45. 378
Absorption ≤ 80% - Executive summary:
Calculated value Jmax = 45. 378
Absorption ≤ 80%
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