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EC number: 276-481-8 | CAS number: 72214-18-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- None
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- Identification: FAT 41001/H TE
Appearance: Blue powder - Water solubility:
- 332 g/L
- Temp.:
- 20 °C
- Remarks on result:
- other: pH is not known
- Details on results:
- None
- Conclusions:
- The water solubility cs of the test item at a temperature of 20 °C was determined to (without correction for the purity): cs = 332 g/L. FAT 41001 is very soluble (> 10000 mg/L).
- Executive summary:
The purpose of the study was determination of the water solubility of FAT 41001/H according to the European Commission Regulation (EC) No.440/2008, A6. Water solubility , flask – method and OECD test guidelines OECD 105 water solubility were used to performed the experiment.
The water solubility cs of the test item at a temperature of 20 °C was determined to (without correction for the purity): cs = 332 g/L. FAT 41001 is very soluble (> 10000 mg/L).
Reference
Preliminary Visual Estimation of the Water Solubility
Amount of the test item in mg |
Total volume in ml |
Appearance of mixture |
104 |
0.1 |
Undissolved |
0.5 |
Dissolved |
The preliminary visual experiments showed that the water solubility of the test item is >208 g/l and <1040 g/l. Therefore the water solubility had to be determined by the “flask method”
Due to the high-water solubility it was tested which amount of the test substance could be stirred in a defined volume of water.
volume of water in mL |
mass of the added test item in gm |
total mass of the test item in g |
Appearance of mixture |
2 |
1.0 |
1.0 |
solution is stirrable |
2 |
+ 0.5 |
1.5 |
solution is stirrable |
2 |
+ 0.5 |
2.0 |
could not be stirred |
2.5 |
-- |
2.0 |
solution is stirrable |
Flask-Method
Experiment |
A |
B |
C |
D(blank) |
Amount of test item(g) |
2 |
2 |
2 |
-- |
Stirring time at 30°C (h) |
24 |
48 |
72 |
72 |
Aliquot of the flasks µl/10/0,45/10 |
10 |
10 |
10 |
10 |
Measured concentration(µg/ml) |
15.26 |
14.16 |
15.37 |
-- |
Water solubility(g/L) |
339 |
315 |
342 |
-- |
Description of key information
The purpose of the study was determination of the water solubility of FAT 41001/H according to the European Commission Regulation (EC) No.440/2008, A6. Water solubility, flask – method and OECD test guidelines OECD 105 water solubility were used to performed the experiment. The water solubility cs of the test item at a temperature of 20 °C was determined to (without correction for the purity): cs = 332 g/L. FAT 41001 is very soluble (> 10000 mg/L).
Key value for chemical safety assessment
- Water solubility:
- 332 g/L
- at the temperature of:
- 20 °C
Additional information
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