Registration Dossier
Registration Dossier
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EC number: 421-450-8 | CAS number: 154702-15-5
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data is from test report
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Year:
- 1 996
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 401 EEC GUIDELINES B.1 , Section 4.1.1
- Principles of method if other than guideline:
- Data is from test report
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 421-450-8
- EC Name:
- -
- Cas Number:
- 154702-15-5
- Molecular formula:
- C44H59N7O5
- IUPAC Name:
- Bis(2-ethylhexyl) 4,4’-{6-[4-tert-butylcarbamoyl)anilino]-1,3,5-triazine-2,4-diyldiimino}dibenzoate
- Reference substance name:
- bis(2-ethylhexyl) 4,4’-{6-[4-tert-butylcarbamoyl) anilino]-1,3,5-triazine-2,4-diyldiimino}dibenzoate
- IUPAC Name:
- bis(2-ethylhexyl) 4,4’-{6-[4-tert-butylcarbamoyl) anilino]-1,3,5-triazine-2,4-diyldiimino}dibenzoate
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- other: SPRAGUE DRAWLEY Crl: CD BR RATS
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: drinking water
- Vehicle:
- other: 0.5% METHYLCELLULOSE WATER SOLUTION
- No. of animals per sex per dose:
- Male: Number of animals: 5;
Female: Number of animals: 5
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- Male: > 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: > 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- Signs of toxicity related to dose levels:
No clinical signs or behavioural alterations were observed
in any rat. No animals died during the observation period. - Gross pathology:
- Effects on organs:
Body weight gains was considered within normal limits for animal of this strain and age. At the autopsy carried out at the end of the observation period no appreciable macroscopic findings were evident in any treated rats.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The Acute toxicity (LD50) values of test material was found to be >2000 mg/kg for male and female rats.
- Executive summary:
The Acute toxicity (LD50) values of test material was found to be >2000 mg/kg for male and female rats.
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