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Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only short abstract available.

Data source

Reference
Reference Type:
publication
Title:
Akrylove Slouleniny A Zdravotni Stav Exponovanicch Osob.
Author:
Kuzelova et al
Year:
1981
Bibliographic source:
Pracov. Lek. 33: 95-99.

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Butyl acrylate
EC Number:
205-480-7
EC Name:
Butyl acrylate
Cas Number:
141-32-2
Molecular formula:
C7H12O2
IUPAC Name:
butyl prop-2-enoate
Test material form:
other: liquid

Results and discussion

Clinical signs:
14/33 (42.3%) employees who were exposed for an average of 5 years to 50 mg/m3 butyl acrylate and 4 - 58 mg/m3 ethyl acrylate complained about nervous disorders. No changes were found in the EEG (electroencephalographic examination).

Applicant's summary and conclusion