Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

BASF (1999) provided results of 72 hr EC50 of >91.5 mg/L (biomass and growth) and 72 hr NOEC of 1.43 mg/L for Scenedesmus subspicatus.  The study was performed according to OECD 201 and GLP.

Key value for chemical safety assessment

EC50 for freshwater algae:
91.5 mg/L
EC10 or NOEC for freshwater algae:
1.43 mg/L

Additional information

A summary of toxicity to aquatic algae is presented in the table below:

 Guideline  Species  Effect Concentration  Reference  Reliability
 /  Several No effects concentration reported. 

NTA has no toxic effects on the growth of algae.

 Brouwer and Terpstra (1994)  4- secondary literature
OECD 201 Scenedesmus subspicatus 72hr EC10 = 22.8 mg/L (growth), 74.8 mg/L (biomass)72hr NOEC = 1.43 mg/L, 1.56 mg/L (conc. not meas.)72 hr EC50 = >91.5 mg/L (biomass and growth) BASF (1999) 1 -reliable without restrictions (GLP)
Equivalent to OECD 201 Scenedesmus capricornutum; Chlorella vulgaris; Scenedesmus subspicatus Scenedesmus capricornutum: LOEC = 5 -50 mg/L (dependent on growth medium); Chlorella vulgaris: LOEC = 5 -80 mg/L (dependent on growth medium); Scenedesmus subspicatus: LOEC = 5 -80 mg/L (dependent on growth medium) Millington et al (1988) 3 -not reliable
  Equivalent to OECD 201 Navicula seminulum 5-d EC50: (flowthrough, soft water) = 143 mg/L(static, soft water) = 198 mg/L(flowthrough, hard water) = 507 mg/L(static, hard water) = 507 mg/L Weaver (1967) 2 - reliable with restrictions
Other Guideline: cell multiplication inhibition test Scenedesmus quadricauda Test with Nitrilotriacetic acid; 8 day toxicity threshold = 8.3 mg/L NTA Bringmann & Kuhn (1977) 3 - unreliable