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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1962
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Purity unknown and method is only partially described.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1962

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol
EC Number:
220-562-2
EC Name:
1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol
Cas Number:
2814-77-9
Molecular formula:
C16H10ClN3O3
IUPAC Name:
1-[(2-chloro-4-nitrophenyl)diazenyl]-2-naphthol
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Test animals

Species:
mouse

Administration / exposure

Route of administration:
oral: gavage
No. of animals per sex per dose:
10

Results and discussion

Effect levels
Key result
Dose descriptor:
LD50
Effect level:
> 10 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
LD50 > 10,000 mg/kg bw
Executive summary:

Three out of ten mouse died from an acute exposure to 10 g/kg bw of C.I. Pigment Red 4.