Registration Dossier
Registration Dossier
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EC number: 221-374-3 | CAS number: 3081-01-4
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: study report does not give sufficient experimental details
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 967
- Report date:
- 1967
Materials and methods
- Principles of method if other than guideline:
- other: acute inhalation toxicity study
- GLP compliance:
- no
- Test type:
- other: acute inhalation toxicity study
Test material
- Reference substance name:
- N-(1,4-dimethylpentyl)-N'-phenylbenzene-1,4-diamine
- EC Number:
- 221-374-3
- EC Name:
- N-(1,4-dimethylpentyl)-N'-phenylbenzene-1,4-diamine
- Cas Number:
- 3081-01-4
- Molecular formula:
- C19H26N2
- IUPAC Name:
- N1-(5-methylhexan-2-yl)-N4-phenylbenzene-1,4-diamine
- Details on test material:
- Santoflex 14
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- whole body
- Vehicle:
- other: unchanged (no vehicle)
- Duration of exposure:
- 6 h
- No. of animals per sex per dose:
- 4
- Control animals:
- not specified
Results and discussion
Any other information on results incl. tables
Average temoerature inside chamber: 76.5 °F
Average relative humidity inside chamber: 60.0 %
Amount of sample to start: 100 g
revovered: 99.8 g
vaporized or left: 0.2 g( 0.2 %)
Mortality: none
All animals survived the six hour exposure as well as the following ten day observation period.
Clinical signs: Some discomfort developed during exposure but there was no weakness of consequence. Nasal and ocular mucosae remained free of inflammation. Occasional irregular breathing was noted. Behavior appeared normal in 24 -hours. The ten day observation period was uneventful.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
