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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

The ready biodegradability of the test item was assessed according to the OECD guideline 301 D “Ready biodegradability: Closed Bottle Test”. Under the test conditions, the percentage of biodegradation of 1,3-diethyl-2-thiourea reached 3 % of the ThOD at the end of the test (28 days) and is thus non readily biodegradable.

 

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

The ready biodegradability of the test item was assessed according to the OECD guideline 301 D “Ready biodegradability: Closed Bottle Test”.


According to the OECD guideline 301, the pass level for ready biodegradability is 60 % of Theoretical Oxygen Demand (ThOD). This level has to be reached in a 10-d window within the 28-d period of the test. The 10-d window begins when the degree of biodegradation has reached 10 % of ThOD and must end before day 28 of the test.


Under the test conditions, the percentage of biodegradation of 1,3-diethyl-2-thiourea reached 3 % of the ThOD at the end of the test (28 days).


According to OECD guideline 301, 1,3-diethyl-2-thiourea is not readily biodegradable.


1,3-diethyl-2-thiourea did not inhibit the micro-organisms as shown by the toxicity control flask where biodegradation percentage is 47% higher than 25 % within 14 days.


 


In addition, using an in-silico approach, the biotic degradation products of the test substance were identified using the EAWAG tool and their persistence profile has been studied with EPISuite (v4.1). None of the identified degradation products is expected to fulfill the P criterion.