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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

Key value for chemical safety assessment

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In a long-term study in compliance with EPA OPP 72-4 the chronic effect of Triclosan on fish was tested. A flow-through system was set up according to the guideline. Fertilised eggs of Oncorhynchus mykiss were exposed to 5 - 80 µg/l Triclosan. The test was terminated after 96 d and the hatching and the survival of juveniles were determined. A NOEC of 34.1 µg/l was reported (Ciba-Geigy 1996, report no. 42726R).

The following table provides an overview on the available reliable data on long-term toxicity to fish.

Reference

RL

Species

Exp.

Effect level

Value

(µg/L)

Nom./

meas.

Test system

Unilever/Ciba Specialty Chemicals (1996). Rep. no. 42726R

2

Onchorhynchus mykiss

96 d

NOEC

34.1

meas.

Fish early-life stage test

BASF SE (2012). Rep. No CSCH01-00222

1

Pimephales promelas

21 d

NOEC

> 13.5 µg/L

meas.

21-d Fish reproduction screen

Tamura et al. (2012)

2

Danio rerio

9 d

NOEC

29

nom.

Fish short-term toxicity test on embryo and sac-fry stages

Tatarazako et al. (2004)

2

Danio rerio

9 d

EC10

150

nom.

Fish short-term toxicity test on embryo and sac-fry stages

Tatarazako et al. (2004)

2

Oryzias latipes

14 d

EC10

160

nom.

Fish short-term toxicity test on embryo and sac-fry stages

Exp.: exposure duration; Meas.: measured; Nom.: nominal; RL: Reliability