Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 233-823-0 | CAS number: 10377-52-3
Long-term toxicity to fish
Administrative data
- Endpoint:
- fish, juvenile growth test
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The presented data have been retrieved from US EPA's ECOTOX Database, Version 4 (2012). This database provides single chemical toxicity information for aquatic and terrestrial life. The concomitant information within the database (such as indentification of guidelines and methods used) is reduced to the necessary minimum and usually not reported. Nevertheless, the toxicity data deposited has been derived from peer-reviewed literature and can therefore be regarded as valid information.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Lithium Chloride: A Flow-Through Embryo-Larval Toxicity Test with the Fathead Minnow, Pimephales promelas Rafinesque.
- Author:
- Long KE, Brown RP Jr., Woodburn KB
- Year:
- 1 998
- Bibliographic source:
- Bull. Environ. Contam. Toxicol. 60, 312-317
- Reference Type:
- secondary source
- Title:
- ECOTOX: Aquatic Report
- Author:
- U.S. EPA
- Year:
- 2 012
- Bibliographic source:
- ECOTOX Database Version 4.0
Materials and methods
- Principles of method if other than guideline:
- A test guideline is not available.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Lithium chloride
- EC Number:
- 231-212-3
- EC Name:
- Lithium chloride
- Cas Number:
- 7447-41-8
- IUPAC Name:
- lithium chloride
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Pimephales promelas
- Details on test organisms:
- - Test organism: Fathead minnow
- Age of fish: < 24 h
Study design
- Test type:
- flow-through
- Water media type:
- freshwater
- Total exposure duration:
- 26 d
Test conditions
- Hardness:
- 56 - 70 mg/L CaCO3
- pH:
- 7.2 - 7.5
Results and discussion
Effect concentrations
- Duration:
- 26 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- Lithium
- Basis for effect:
- growth rate
- Remarks:
- (length)
- Remarks on result:
- other: equivalent to 1.12 mg/L Li3PO4
- Details on results:
- Conversion:
0.2 mg/L : 6.94 u (atomic weight of Li) = 0.029 mmol/L
0.029 mmol/L : 3 = 0.0097
0.0097 x 115.82 (molecular weight of Li3PO4) = 1.12 mg/L
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
