1,2,4-trichlorobenzene

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

20 °C

Vapour pressure:

0.26 hPa

Executive summary:

ROEMPP Online, 2009

The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.

Reference 2

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection of data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

38.4 °C

Vapour pressure:

0.13 kPa

Temp.:

67.3 °C

Vapour pressure:

0.67 kPa

Temp.:

81.7 °C

Vapour pressure:

1.33 kPa

Temp.:

97.2 °C

Vapour pressure:

2.67 kPa

Temp.:

114.8 °C

Vapour pressure:

5.33 kPa

Temp.:

125.7 °C

Vapour pressure:

8 kPa

Temp.:

140 °C

Vapour pressure:

13.3 kPa

Temp.:

162 °C

Vapour pressure:

26.7 kPa

Temp.:

187.7 °C

Vapour pressure:

53.3 kPa

Temp.:

213.5 °C

Vapour pressure:

101.3 kPa

Executive summary:

Ullmann, 2006

Data of 1,2,4-trichlorobenzene on vapour pressure range from 130 Pa at 38.4 °C and 101,300 Pa at 213.5 °C.

Reference 3

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Remarks:

Only secondary literature

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

25 °C

Vapour pressure:

0.46 mm Hg

Conversion from mm Hg to Pa: 1 mm Hg = 133 Pa

Executive summary:

Shiu, 1997

The vapour pressure of 1,2,4-trichlorobenzene was reported as 61 Pa at 25°C.

Reference 4

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

25 °C

Vapour pressure:

0.453 hPa

Executive summary:

WHO, 1991

The vapour pressure of 1,2,4-trichlorobenzene was reported as 45.3 Pa at 25°C.

Reference 5

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Remarks:

Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

25 °C

Vapour pressure:

0.38 hPa

Executive summary:

Rippen, 1991, EPA, 1985, UBA, 1984, Ware 1977

The vapour pressure of 1,2,4-trichlorobenzene was reported as 38 Pa at 25°C.

Reference 6

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Remarks:

Only secondary literature

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

20 °C

Vapour pressure:

0.31 hPa

Executive summary:

Rippen, 1991

The vapour pressure of 1,2,4-trichlorobenzene was reported as 31 Pa at 20°C.

Reference 7

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

38.4 °C

Vapour pressure:

1.3 hPa

Executive summary:

Howard, 1989, UBA 1984

The vapour pressure of 1,2,4-trichlorobenzene was reported as 130 Pa at 38.4 °C.

Reference 8

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

50 °C

Vapour pressure:

2.02 hPa

Executive summary:

Auer, 1988

The vapour pressure of 1,2,4-trichlorobenzene was reported as 202 Pa at 50°C.

Reference 9

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed source, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

20 °C

Vapour pressure:

0.26 hPa

Executive summary:

Auer, 1988, Hommel, 1994

The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.

Reference 10

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

30 °C

Vapour pressure:

0.54 hPa

Executive summary:

Auer, 1988

The vapour pressure of 1,2,4-trichlorobenzene was reported as 54 Pa at 30°C.

Reference 11

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

20 °C

Vapour pressure:

26.3 Pa

Executive summary:

Korte, 1986

The vapour pressure of 1,2,4-trichlorobenzene was reported as 26.3 Pa at 20°C.

Reference 12

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Original report not available

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

25 °C

Vapour pressure:

0.56 hPa

Executive summary:

Hooftman, 1982

The vapour pressure of 1,2,4-trichlorobenzene was reported as 56 Pa at 25°C.

Reference 13

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

20 °C

Vapour pressure:

0.32 hPa

Executive summary:

GSF, 1982

The vapour pressure of 1,2,4-trichlorobenzene was reported as 32 Pa at 20°C.

Reference 14

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.

Principles of method if other than guideline:

secondary peer reviewed scoure, valid collection af data

GLP compliance:

not specified

Type of method:

other: no data

Specific details on test material used for the study:

analytical purity: not specified

Temp.:

20 °C

Vapour pressure:

0.4 hPa

Executive summary:

Beilstein, 1978

The vapour pressure of 1,2,4-trichlorobenzene was reported as 40 Pa at 20°C.

Description of key information

The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.

 

The vapor pressure of 1,2,4-trichlorobenzene was determined in a series of experimental studies and is 26 Pa to 61 Pa in the temperature range from 20 °C to 25 °C. The mean value of 43.5 Pa at room temperature was chosen as key value for chemical safety assessment.
Experiments at temperatures between 38.4 °C and 213.5 °C show vapor pressures between 130 Pa and 101300 Pa.

 

ROEMPP Online, 2009
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.

Ullmann, 2006
Data of 1,2,4-trichlorobenzene on vapour pressure range from 130 Pa at 38.4 °C and 101,300 Pa at 213.5 °C.

Shiu, 1997
The vapour pressure of 1,2,4-trichlorobenzene was reported as 61 Pa at 25°C.

WHO, 1991
The vapour pressure of 1,2,4-trichlorobenzene was reported as 45.3 Pa at 25°C.

Rippen, 1991, EPA, 1985, UBA, 1984, Ware 1977
The vapour pressure of 1,2,4-trichlorobenzene was reported as 38 Pa at 25°C.

Rippen, 1991
The vapour pressure of 1,2,4-trichlorobenzene was reported as 31 Pa at 20°C.

Howard, 1989, UBA 1984
The vapour pressure of 1,2,4-trichlorobenzene was reported as 130 Pa at 38.4 °C.

Auer, 1988
The vapour pressure of 1,2,4-trichlorobenzene was reported as 202 Pa at 50°C.

Auer, 1988, Hommel, 1994
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.

 

Korte, 1986
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26.3 Pa at 20°C.

Hooftman, 1982
The vapour pressure of 1,2,4-trichlorobenzene was reported as 56 Pa at 25°C.

GSF, 1982
The vapour pressure of 1,2,4-trichlorobenzene was reported as 32 Pa at 20°C.

Key value for chemical safety assessment

Vapour pressure:

43.5 Pa

at the temperature of:

20 °C