Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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Reaction mass of Cobaltate(3-), bis[2-[[[3-[2-[1-[[(2-chlorophenyl)amino]carbonyl]-2-(oxo-κO)propyl]diazenyl-κN1]-4-(hydroxy-κO)phenyl]sulfonyl]amino]benzoato(3-)]-, sodium (1:3) and tetrasodium bis[2-[[[3-[[1-[(2-chloroanilino)carbonyl]-2-oxopropyl]azo]-4-hydroxyphenyl]sulphonyl]amino]benzoato(3-)]cobaltate(4-)
EC number: 941-792-6 | CAS number: -
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1977
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: MITI (guideline Nr. not specified)
- GLP compliance:
- no
- Specific details on test material used for the study:
- None
- Radiolabelling:
- not specified
- Details on sampling:
- no data
- Vehicle:
- not specified
- Details on preparation of test solutions, spiked fish food or sediment:
- no data
- Test organisms (species):
- Cyprinus carpio
- Details on test organisms:
- TEST ORGANISM
- Common name: common carp - Route of exposure:
- aqueous
- Test type:
- not specified
- Water / sediment media type:
- not specified
- Remarks:
- freshwater
- Total exposure / uptake duration:
- 8 wk
- Hardness:
- no data
- Test temperature:
- no data
- pH:
- no data
- Dissolved oxygen:
- no data
- TOC:
- no data
- Salinity:
- no data
- Details on test conditions:
- no data
- Nominal and measured concentrations:
- Nominal: 0, 0.01 and 0.001 ppm = 1 and 10 µg/L
- Reference substance (positive control):
- no
- Conc. / dose:
- 0.001 other: ppm
- Type:
- BCF
- Value:
- < 2 143 L/kg
- Remarks on result:
- other: Conc.in environment / dose:1 ppb
- Conc. / dose:
- 0.01 other: ppm
- Type:
- other: AF
- Value:
- < 214 L/kg
- Remarks on result:
- other: Conc.in environment / dose:10 ppb
- Details on kinetic parameters:
- no data
- Metabolites:
- no data
- Results with reference substance (positive control):
- no data
- Details on results:
- no data
- Reported statistics:
- no data
- Validity criteria fulfilled:
- no
- Conclusions:
- Under the conditions of a MITI test, the bioconcentration factor (= concentration in fish / concentration in water) in carp at 1 µg/L was <2143 L/kg. At 10 µg/L, it was <214 L/kg. These results suggest that the test substance has a low bioconcentration potential in fish.
- Executive summary:
A study was conducted to assess the bioconcentration potential of the test substance (of ca. 89 % purity) in common carp (Cyprinus carpio) according to the MITI method. Fish were exposed at 1 and 10 ppb (= 1 and 10 µg/L) for 8 weeks. Average concentrations in water and fish were recorded weekly. At 1 µg/L, the bioconcentration factor (= concentration in fish / concentration in water) was <2143 L/kg. At 10 µg/L, it was <214 L/kg. These results suggest that the test substance has a low bioconcentration potential in fish.
Reference
| Table 1: Results at 1 µg/L exposure concentration | |||
| Time | Concentration in water (µg/L) | Concentration in fish (µg/kg) | BCF* |
| Week 1 | < 36 | < 2143 | < 2143 |
| Week 2 | < 36 | < 2143 | < 2143 |
| Week 3 | < 36 | < 2143 | < 2143 |
| Week 4 | < 36 | < 2143 | < 2143 |
| Week 5 | < 36 | < 2143 | < 2143 |
| Week 6 | < 36 | < 2143 | < 2143 |
| Week 7 | < 36 | < 2143 | < 2143 |
| Week 8 | < 36 | < 2143 | < 2143 |
| * Calculated using the nominal concentration of 1 µg/L | |||
| Table 2: Results at 10 µg/L exposure concentration | |||
| Time | Concentration in water (µg/L) | Concentration in fish (µg/kg) | BCF* |
| Week 1 | < 36 | < 2143 | < 214 |
| Week 2 | < 36 | < 2143 | < 214 |
| Week 3 | < 36 | < 2143 | < 214 |
| Week 4 | < 36 | < 2143 | < 214 |
| Week 5 | < 36 | < 2143 | < 214 |
| Week 6 | < 36 | < 2143 | < 214 |
| Week 7 | < 36 | < 2143 | < 214 |
| Week 8 | < 36 | < 2143 | < 214 |
| * Calculated using the nominal concentration of 10 µg/L | |||
Description of key information
A study was conducted to assess the bioconcentration potential of the test substance (of ca. 89 % purity) in common carp (Cyprinus carpio) according to the MITI method.
Fish were exposed at 1 and 10 ppb (= 1 and 10 µg/L) for 8 weeks. Average concentrations in water and fish were recorded weekly. At 1 µg/L, the bioconcentration factor (= concentration in fish / concentration in water) was <2143 L/kg. At 10 µg/L, it was <214 L/kg. These results suggest that the test substance has a low bioconcentration potential in fish.
Key value for chemical safety assessment
- BCF (aquatic species):
- 214 L/kg ww
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
