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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
< 0.05 µg/L
Temp.:
20 °C
Remarks on result:
other: The substance was not detectable without solubilizer.
Water solubility:
794 µg/L
Temp.:
20 °C
Remarks on result:
other: 1% acetonitrile was used as solubilizer.
Conclusions:
Interpretation of results: insoluble (< 0.1 mg/L)
The water solubility of the substance could not be detected without solubilizer and is reported to be < 0.05 µg/l. With 1% acetonitrile as solubilizer a water solubility of 794 µg/l could be detected.
Executive summary:

The water solubility of the substance was investigated using the Council Regulation A.6, which is in most parts equivalent to the OECD guideline 105. The water solubility of the substance could not be detected without solubilizer and is reported to be < 0.05 µg/l at 20°C. With 1% acetonitrile as solubilizer a water solubility of 794 µg/l at 20°C could be detected.

Description of key information

The water solubility of the substance was investigated using the Council

Regulation A.6, which is in most parts equivalent to the OECD guideline 105. The water solubility of the substance could not be detected without solubilizer and is reported to be < 0.05 µg/l at 20°C. With 1% acetonitrile as solubilizer a water solubility of 794 µg/l at 20°C could be detected.

Key value for chemical safety assessment

Water solubility:
794 µg/L
at the temperature of:
20 °C

Additional information

The water solubility was determined using 1% acetonitrile as solubilizer.