Substance evaluation - CoRAP

For each substance, the table shows the evaluating Member State, the year of evaluation and a short description of the concern which led to it being placed on the list.

Community rolling action plan (CoRAP): The community rolling action plan covers three consecutive years and is updated mid of March every year. From this it follows that substances in the table below with the column ‘Year’ indicating a current or future year, are those that have been prioritised for evaluation, and are effectively on the current CoRAP.

Documents to do with substance evaluation are also available here. They include: documents justifying selection of the substances, decisions to request more information. Member States' conclusions and Member States' final evaluation reports are included for substances for which evaluation has been finalised.

Notes to the Substance Evaluation and CoRAP table

Where two Members States are indicated, this is a joint evaluation. The first Member State mentioned leads the Evaluation and is the responsible competent authority in the meaning of Article 45(2) of REACH.
The substance public name is used. In most of the cases it is the name as disseminated on the ECHA website.
When the EC Number is not available, the number assigned to substance by ECHA after the inquiry process is used.
When the substances are included in the CoRAP, they have not yet been evaluated and thus the concern is indicative and not exhaustive or conclusive.
Contact details of the evaluating Member States are provided for all the substance included.
Please note that the justification document explains the grounds of the initial concerns that triggered the inclusion of the substance in the CoRAP for further clarification under substance evaluation. The justification document is based on a preliminary screening of the substance and is without prejudice to the outcome of the substance evaluation.

Legend:

Suspected PBT/vPvB: Potentially Persistent, Bioaccumulative and Toxic/very Persistent and very Bioaccumulative.
CMR: generic term for known carcinogenic and/or mutagenic and/or reprotoxic properties (according to CLP harmonised or registrant self-classification or CLP Inventory). The concern can refer to C, M, R or a combination of those.
Suspected CMR: generic term for suspected carcinogenic and/or mutagenic and/or reprotoxic properties (not classified according to CLP harmonised or registrant self-classification). The concern can refer to (suspected) C, M, R or a combination of those.
Sensitiser: generic term for known sensitising properties (according to CLP harmonised or registrant self-classification or CLP Inventory).
Suspected sensitiser: generic term for suspected sensitising properties (not classified according to CLP harmonised or registrant self-classification).
RCR: Risk Characterisation Ratio

Last updated 13 December 2019. Database contains 375 unique substances/entries.

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Showing 1 - 200 of 376 results.

Substance name	EC / List no	CAS no	Year	Evaluating Member State	Initial grounds for concern	Status
(-)-pin-2(10)-ene	242-060-2	18172-67-3	2014	Greece	Sensitiser Consumer use High (aggregated) tonnage Wide dispersive use	Concluded	Details
(1-methylethyl)-1,1'-biphenyl	247-156-8	25640-78-2		Germany	Suspected PBT/vPvB Wide dispersive use	Not started	Details
1,1'-(ethane-1,2-diyl)bis[pentabromobenzene]	284-366-9	84852-53-9	2012	Sweden	Suspected PBT/vPvB High (aggregated) tonnage Wide dispersive use	Information requested	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene]	306-832-3	97416-84-7	2017	Germany	Potential endocrine disruptor Suspected PBT/vPvB Exposure of environment	Ongoing	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene]	244-617-5	21850-44-2	2017	Germany	Potential endocrine disruptor Suspected PBT/vPvB High (aggregated) tonnage	Ongoing	Details
1,1'-iminodipropan-2-ol	203-820-9	110-97-4	2013	Czech Republic	Suspected CMR Suspected Sensitiser Consumer use Exposure of workers High RCR Wide dispersive use	Concluded	Details
1,1,1,3,3,3-hexamethyldisilazane	213-668-5	999-97-3	2014	Spain	High (aggregated) tonnage High RCR	Concluded	Details
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane	241-867-7	17928-28-8	2020	Norway	Suspected PBT/vPvB Wide dispersive use	Not started	Details
1,1,1,3,5,5,5-heptamethyltrisiloxane	217-496-1	1873-88-7	2020	Norway	Suspected PBT/vPvB	Not started	Details
1,2,4-triazole	206-022-9	288-88-0	2015	Belgium	Suspected CMR Other hazard based concern Exposure of environment High (aggregated) tonnage Other exposure/risk based concern Wide dispersive use	Ongoing	Details
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters	271-082-5	68515-40-2	2014	Denmark	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Information requested	Details
1,2-benzenedicarboxylic acid, di-C10-12-branched alkyl esters	700-989-5	-	2014	Denmark	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Ongoing	Details
1,2-benzenedicarboxylic acid, di-C11-14-branched alkyl es-ters, C13-rich	271-089-3	68515-47-9	2014	Denmark	High (aggregated) tonnage Other exposure/risk based concern Suspected CMR	Ongoing	Details
1,2-benzenedicarboxylic acid, di-C9-11-branched and linear alkyl esters	271-085-1	68515-43-5	2014	Denmark	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Ongoing	Details
1,2-dichlorobenzene	202-425-9	95-50-1	2013	Hungary	Suspected CMR High (aggregated) tonnage Wide dispersive use	Conclusion under preparation	Details
1,3,5-trioxane	203-812-5	110-88-3	2013	Poland	Suspected CMR Suspected PBT/vPvB Suspected Sensitiser Exposure of environment High (aggregated) tonnage Wide dispersive use	Concluded	Details
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC)	219-514-3	2451-62-9	2015	Poland	CMR Suspected PBT/vPvB Consumer use Exposure of environment Exposure of workers Wide dispersive use	Concluded	Details
1,3-diethyl-2-thiourea	203-308-5	105-55-5	2019	Poland	Suspected Carcinogenic Suspected Sensitiser Consumer use Exposure of environment Exposure of workers Wide dispersive use	Ongoing	Details
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione	258-904-8	53988-10-6	2018	Germany	Potential endocrine disruptor Exposure of environment	Ongoing	Details
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt	262-872-0	61617-00-3	2018	Germany	Potential endocrine disruptor Exposure of environment	Ongoing	Details
1,3-diisopropylbenzene	202-773-1	99-62-7	2020	Bulgaria	Suspected Reprotoxic Suspected PBT/vPvB Exposure of workers	Not started	Details
1,3-dioxolane	211-463-5	646-06-0	2016	Germany	Suspected Mutagenic Suspected Reprotoxic Consumer use Exposure of sensitive populations High (aggregated) tonnage Wide dispersive use	Ongoing	Details
1,3-diphenylguanidine	203-002-1	102-06-7	2012	France	CMR High (aggregated) tonnage High RCR	Ongoing	Details
1,4,5,6,7,7-hexachloro-8,9,10-trinorborn-5-ene-2,3-dicarboxylic anhydride	204-077-3	115-27-5	2013	France	CMR Suspected PBT/vPvB Suspected Sensitiser Exposure of environment Exposure of workers	Information requested	Details
1,4-Benzenediamine, N,N'-mixed phenyl and tolyl derivatives (BENPAT)	273-227-8	68953-84-4	2013	Germany	Suspected PBT/vPvB Consumer use High (aggregated) tonnage Wide dispersive use	Information requested	Details
1,4-diisopropylbenzene	202-826-9	100-18-5	2020	Bulgaria	Suspected Reprotoxic Suspected PBT/vPvB Exposure of workers	Not started	Details
1-(2-hydroxy-5-nonyl(branched)-phenyl)ethanone oxime	627-083-1	244235-47-0	2015	Spain	Suspected PBT/vPvB High (aggregated) tonnage	Concluded	Details
1-(4-methyl-2-nitrophenylazo)-2-naphthol	219-372-2	2425-85-6	2019	Germany	Suspected Carcinogenic Suspected Mutagenic Suspected Reprotoxic Suspected PBT/vPvB Exposure of environment	Ongoing	Details
1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one EC No. 216-133-4 and EC No. 244-240-6 show/hide 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one EC / List no: 216-133-4 \| CAS no: 1506-02-1 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one EC / List no: 244-240-6 \| CAS no: 21145-77-7	-	-	2020	Germany	Potential endocrine disruptor High (aggregated) tonnage	Not started	Details
1-[(2,4-dinitrophenyl)azo]-2-naphthol	222-429-4	3468-63-1	2019	Germany	Suspected Carcinogenic Suspected Reprotoxic Suspected PBT/vPvB Exposure of workers Wide dispersive use	Ongoing	Details
1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol	220-562-2	2814-77-9	2019	Germany	Suspected Carcinogenic Suspected Mutagenic Suspected Reprotoxic Suspected PBT/vPvB Exposure of environment	Ongoing	Details
1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)propane-1,3-dione	274-581-6	70356-09-1	2015	Germany	Suspected PBT/vPvB Consumer use Exposure of environment High (aggregated) tonnage Wide dispersive use	Information requested	Details
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone	216-475-4	1594-08-7	2019	Belgium	Suspected PBT/vPvB	Ongoing	Details
1-isocyanato-2(or 4)-(4-isocyanatobenzyl)benzene and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propylene glycol	701-029-8	-		Estonia	CMR Sensitiser Consumer use Wide dispersive use	Not started	Details
1-phenylethanol	202-707-1	98-85-1	2019	Italy	Suspected Carcinogenic Suspected Mutagenic Consumer use Exposure of workers Wide dispersive use	Ongoing	Details
10-undecenyl 2-cyano-3,3-diphenylpropenoate	700-604-0	947701-81-7		Finland	Suspected PBT/vPvB Consumer use	Not started	Details
2,2',2''-nitrilotriethanol	203-049-8	102-71-6	2014	United Kingdom	Suspected CMR Suspected Sensitiser Other hazard based concern Consumer use Exposure of workers High (aggregated) tonnage Wide dispersive use	Concluded	Details
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether	926-564-6	-	2016	Germany	Potential endocrine disruptor Suspected PBT/vPvB Exposure of environment	Information requested	Details
2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bisoxirane	216-823-5	1675-54-3	2015	Denmark	Suspected CMR Potential endocrine disruptor Consumer use High (aggregated) tonnage Wide dispersive use	Follow-up	Details
2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine)	229-962-1	6864-37-5	2015	Germany	Potential endocrine disruptor	Ongoing	Details
2,2'-Iminodiethanol	203-868-0	111-42-2	2012	Germany	Suspected CMR High (aggregated) tonnage Wide dispersive use	Information requested	Details
2,2'-methyliminodiethanol	203-312-7	105-59-9	2013	United Kingdom	Suspected CMR High (aggregated) tonnage High RCR Wide dispersive use	Concluded	Details
2,2'-oxydiethanol	203-872-2	111-46-6	2015	Hungary	Suspected CMR Other hazard based concern Consumer use High (aggregated) tonnage Wide dispersive use	Concluded	Details
2,2,6,6-tetrabromo-4,4-isopropylidenediphenol	201-236-9	79-94-7	2015	Denmark	Suspected Reprotoxic Potential endocrine disruptor Suspected PBT/vPvB Consumer use Exposure of environment Exposure of workers High (aggregated) tonnage Wide dispersive use	Information requested	Details
2,2-dimethylpropan-1-ol, tribromo derivative	253-057-0	36483-57-5	2021	Denmark	Suspected Carcinogenic Suspected Mutagenic	Not started	Details
2,2′,6,6′-Tetra-tert-butyl-4,4′- methylenediphenol	204-279-1	118-82-1	2014	Austria	Suspected CMR Potential endocrine disruptor Suspected PBT/vPvB Suspected Sensitiser Consumer use Exposure of environment Exposure of workers Wide dispersive use	Information requested	Details
2,3-epoxypropyl neodecanoate	247-979-2	26761-45-5	2015	Denmark	Suspected CMR Suspected Sensitiser Consumer use Exposure of workers High (aggregated) tonnage Wide dispersive use	Follow-up	Details
2,3-epoxypropyl o-tolyl ether	218-645-3	2210-79-9	2016	Denmark	Mutagenic	Information requested	Details
2,4,6-tri-tert-butylphenol	211-989-5	732-26-3	2017	Belgium	Suspected PBT/vPvB Exposure of environment	Concluded	Details
2,4,6-tribromophenol	204-278-6	118-79-6	2012	Norway	CMR Suspected PBT/vPvB High (aggregated) tonnage High RCR Wide dispersive use	Concluded	Details
2,4,6-trichloro-1,3,5-triazine	203-614-9	108-77-0	2017	Poland	Suspected Reprotoxic Suspected PBT/vPvB Exposure of environment High (aggregated) tonnage	Concluded	Details
2,4-di-tert-butylphenol	202-532-0	96-76-4	2017	Belgium	Suspected CMR Potential endocrine disruptor Consumer use Wide dispersive use	Information requested	Details
2,5,7,10,11,14-hexaoxa-1,6-distibabicyclo[4.4.4]tetradecane	249-820-2	29736-75-2	2018	Germany	Suspected Carcinogenic Suspected Reprotoxic Other hazard based concern Exposure of workers	Ongoing	Details
2,5-di-tert-pentylhydroquinone	201-222-2	79-74-3	2014	Italy	Suspected PBT/vPvB High RCR	Follow-up	Details
2,6,10-Trimethyldodecane (Farnesane)	622-542-2	3891-98-3	2020	Austria	Suspected Mutagenic Suspected PBT/vPvB Suspected Sensitiser Consumer use Exposure of environment Exposure of workers	Not started	Details
2,6-di-tert-butyl-p-cresol	204-881-4	128-37-0	2016	France	Potential endocrine disruptor Exposure of sensitive populations Exposure of workers High (aggregated) tonnage Wide dispersive use	Ongoing	Details
2,9-dimethylanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone	226-866-1	5521-31-3	2021	Belgium	Suspected PBT/vPvB	Not started	Details
2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether	200-076-7	51-03-6		Sweden	Potential endocrine disruptor Suspected PBT/vPvB Consumer use Wide dispersive use	Not started	Details
2-(2H-benzotriazol-2-yl)-p-cresol	219-470-5	2440-22-4	2016	Czech Republic	Sensitiser Consumer use Exposure of workers High RCR Wide dispersive use	Concluded	Details
2-(4-tert-butylbenzyl)propionaldehyde	201-289-8	80-54-6	2012	Sweden	CMR Consumer use Wide dispersive use	Ongoing	Details
2-(phenylmethoxy)naphthalene	405-490-3	613-62-7	2012	Czech Republic	Other hazard based concern High (aggregated) tonnage	Concluded	Details
2-[(2-methoxy-4-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	228-768-4	6358-31-2	2019	Italy	Suspected PBT/vPvB Exposure of environment High (aggregated) tonnage Wide dispersive use	Ongoing	Details
2-[(4-chloro-2-nitrophenyl)azo]-N-(2-chlorophenyl)-3-oxobutyramide	229-355-1	6486-23-3	2019	Italy	Suspected PBT/vPvB Exposure of environment High (aggregated) tonnage Wide dispersive use	Ongoing	Details
2-[(4-methoxy-2-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	229-419-9	6528-34-3	2019	Italy	Suspected PBT/vPvB Exposure of environment High (aggregated) tonnage Wide dispersive use	Ongoing	Details
2-[4-[2-[4-(2-hydroxyethoxy)phenyl]propan-2-yl]phenoxy]ethanol 1 - 4.5 moles ethoxylated	500-082-2	32492-61-8	2021	France	Suspected Mutagenic Potential endocrine disruptor Exposure of environment High (aggregated) tonnage Wide dispersive use	Not started	Details
2-[methyl[(nonafluorobutyl) sulpho-nyl]amino]ethyl acrylate	266-733-5	67584-55-8	2018	Germany	Suspected PBT/vPvB Other hazard based concern Exposure of environment Wide dispersive use	Concluded	Details
2-aminoethanol	205-483-3	141-43-5	2014	United Kingdom	Suspected Sensitiser High (aggregated) tonnage Wide dispersive use	Concluded	Details
2-bromo-3,3,3-trifluoroprop-1-ene	627-872-0	1514-82-5	2019	Spain	Suspected Reprotoxic Potential endocrine disruptor	Ongoing	Details
2-Ethoxy-3,3,4,4,5-pentafluoro-2,5-bis[(1,2,2,2-tetrafluoro-1-trifluoromethyl)ethyl] tetrahydrofuran	484-410-9	-	2019	Spain	Suspected PBT/vPvB	Ongoing	Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate	239-701-3	15625-89-5	2014	France	Sensitiser Exposure of workers High RCR Wide dispersive use	Concluded	Details
2-ethylhexan-1-ol	203-234-3	104-76-7	2014	Poland	Suspected CMR Consumer use High (aggregated) tonnage High RCR Wide dispersive use	Concluded	Details
2-ethylhexanoic acid	205-743-6	149-57-5	2012	Spain	CMR Consumer use High (aggregated) tonnage High RCR Wide dispersive use	Concluded	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	248-227-6	27107-89-7	2021	Netherlands	Potential endocrine disruptor	Not started	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-xoethyl]thio]-4-methyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	260-828-5	57583-34-3	2015	Netherlands	CMR High (aggregated) tonnage	Suspended	Details
2-ethylhexyl acetate	203-079-1	103-09-3	2015	Belgium	Suspected CMR Consumer use Wide dispersive use	Concluded	Details
2-ethylhexyl salicylate	204-263-4	118-60-5	2020	Germany	Potential endocrine disruptor	Not started	Details
2-Ethylhexyl trans-4-methoxycinnamate	629-661-9	83834-59-7	2016	Germany	Potential endocrine disruptor Suspected PBT/vPvB Consumer use Exposure of environment High (aggregated) tonnage Other exposure/risk based concern Wide dispersive use	Information requested	Details
2-furaldehyde	202-627-7	98-01-1	2021	Denmark	Suspected Carcinogenic Suspected Mutagenic Exposure of workers High (aggregated) tonnage Wide dispersive use	Not started	Details
2-hydroxyethyl methacrylate	212-782-2	868-77-9	2014	France	Suspected CMR Sensitiser Consumer use High (aggregated) tonnage High RCR Wide dispersive use	Ongoing	Details
2-methylpropan-2-ol	200-889-7	75-65-0	2013	United Kingdom	Suspected CMR Consumer use High (aggregated) tonnage High RCR Wide dispersive use	Concluded	Details
3,3'-dimethylbiphenyl-4,4'-diyl diisocyanate	202-112-7	91-97-4	2013	France	Suspected CMR Suspected PBT/vPvB Sensitiser Consumer use	Concluded	Details
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl acrylate	241-527-8	17527-29-6	2016	Germany	Potential endocrine disruptor Suspected PBT/vPvB Other hazard based concern Exposure of environment Wide dispersive use	Information requested	Details
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl methacrylate	218-407-9	2144-53-8	2016	Germany	Potential endocrine disruptor Suspected PBT/vPvB Other hazard based concern Exposure of environment Wide dispersive use	Information requested	Details
3,5,5-trimethylcyclohex-2-enone	201-126-0	78-59-1	2013	France	CMR Exposure of workers High (aggregated) tonnage Wide dispersive use	Follow-up	Details
3,5,5-trimethylhexanoic acid	221-975-0	3302-10-1	2020	Spain	Suspected Reprotoxic Exposure of workers	Not started	Details
3,5-dimethylpyrazole	200-657-5	67-51-6	2020	Spain	Reprotoxic High RCR	Not started	Details
3-(4-tert-butylphenyl)propion aldehyde	242-016-2	18127-01-0	2020	Sweden	Suspected Reprotoxic Consumer use Exposure of workers Wide dispersive use	Not started	Details
3-({[(4-methylphenyl)sulfonyl]carbamoyl}amino)phenyl 4-methylbenzenesulfonate; N-(p-toluenesulfonyl)-N'-(3-(p-toluenesulfonyloxy)phenyl)urea	432-520-2	232938-43-1	2020	Belgium	Suspected Reprotoxic Potential endocrine disruptor	Not started	Details
3-aminopropyldimethylamine	203-680-9	109-55-7	2014	Austria	Sensitiser Exposure of workers High (aggregated) tonnage Wide dispersive use	Ongoing	Details
3-ethoxy-1,1,1,2,3,4,4,5,5,6,6,6-dodecafluoro-2-(trifluoromethyl)-hexane	435-790-1	297730-93-9	2018	Spain	Suspected PBT/vPvB Exposure of environment Wide dispersive use	Ongoing	Details
3-methyl-1,5-pentanediyl diacrylate	264-727-7	64194-22-5	2021	Slovenia	Suspected Carcinogenic Exposure of workers Wide dispersive use	Not started	Details
3-methylbutan-1-ol	204-633-5	123-51-3	2020	Poland	Suspected Carcinogenic Suspected Reprotoxic Suspected Sensitiser Consumer use Exposure of workers	Not started	Details
3-methylpyrazole	215-925-7	1453-58-3	2018	Belgium	Suspected Reprotoxic Potential endocrine disruptor Exposure of environment Wide dispersive use	Ongoing	Details
3-trimethoxysilylpropyl methacrylate	219-785-8	2530-85-0	2015	Ireland	Suspected Sensitiser Consumer use Exposure of workers High (aggregated) tonnage Wide dispersive use	Follow-up	Details
3a,4,7,7a-tetrahydro-4,7-methanoindene	201-052-9	77-73-6	2016	France	Suspected Reprotoxic Exposure of workers High (aggregated) tonnage High RCR	Ongoing	Details
4,4'-(1,3-phenylene-bis(1-methylethylidene))bisphenol	428-970-4	13595-25-0	2014	Belgium	Suspected PBT/vPvB Other hazard based concern Consumer use Exposure of environment	Concluded	Details
4,4'-[(isopropylidene)bis (p-phenyleneoxy)]diphthalic dianhydride	253-781-7	38103-06-9	2013	Germany	Suspected PBT/vPvB High (aggregated) tonnage	Concluded	Details
4,4'-isopropylidenediphenol Bisphenol A; BPA	201-245-8	80-05-7	2012	Germany	Potential endocrine disruptor Consumer use High (aggregated) tonnage Wide dispersive use	Concluded	Details
4,4'-methylene bis(dibutyldithiocarbamate)	233-593-1	10254-57-6	2020	Germany	Suspected PBT/vPvB	Not started	Details
4,4'-methylenebis[N,N-bis(2,3-epoxypropyl)aniline]	249-204-3	28768-32-3	2013	Denmark	CMR Wide dispersive use	Information requested	Details
4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol	701-276-1	-		Estonia	CMR Suspected PBT/vPvB Sensitiser Consumer use High (aggregated) tonnage Wide dispersive use	Not started	Details
4,4'-propane-2,2-diyldiphenol, polymer with 2-methyloxirane 1 - 4.5 moles propoxylated	500-097-4	37353-75-6	2013	Denmark	Suspected CMR High (aggregated) tonnage Wide dispersive use	Conclusion under preparation	Details
4,4'-sulfonyldiphenol	201-250-5	80-09-1	2014	Belgium	Suspected CMR Potential endocrine disruptor High (aggregated) tonnage	Information requested	Details
4,4’-methylenediphenyl diisocyanate	202-966-0	101-68-8	2013	Estonia	CMR Suspected PBT/vPvB Sensitiser Consumer use Wide dispersive use	Concluded	Details
4-(4-isopropoxyphenylsulfonyl)phenol	405-520-5	95235-30-6	2021	Belgium	Potential endocrine disruptor Other exposure/risk based concern	Not started	Details
4-hydroxybenzoic acid	202-804-9	99-96-7	2014	Czech Republic	Suspected CMR Potential endocrine disruptor Consumer use High (aggregated) tonnage	Concluded	Details
4-methylanisole	203-253-7	104-93-8	2012	Ireland	CMR Consumer use High RCR Wide dispersive use	Concluded	Details
4-tert-butylphenol	202-679-0	98-54-4	2014	Germany	Potential endocrine disruptor High (aggregated) tonnage	Ongoing	Details
4-tert-butylpyrocatechol	202-653-9	98-29-3	2018	Poland	Suspected Mutagenic Potential endocrine disruptor Suspected PBT/vPvB Sensitiser Exposure of environment Exposure of workers	Concluded	Details
6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol	204-327-1	119-47-1	2016	Denmark	Suspected Reprotoxic Potential endocrine disruptor	Concluded	Details
6,6'-di-tert-butyl-4,4'-butylidenedi-m-cresol	201-618-5	85-60-9	2019	France	Suspected Reprotoxic Potential endocrine disruptor Suspected PBT/vPvB Consumer use Exposure of environment Exposure of workers Wide dispersive use	Ongoing	Details
6,6'-di-tert-butyl-4,4'-thiodi-m-cresol	202-525-2	96-69-5	2015	Austria	Suspected CMR Potential endocrine disruptor Suspected PBT/vPvB Sensitiser Consumer use Wide dispersive use	Information requested	Details
7-oxabicyclo[4.1.0]hept-3-ylmethyl 7-oxabicyclo [4.1.0]heptane-3-carboxylate	219-207-4	2386-87-0	2013	Ireland	Suspected CMR Sensitiser Exposure of workers High RCR	Concluded	Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	246-678-3	25155-25-3	2015	Netherlands	Suspected PBT/vPvB High (aggregated) tonnage Wide dispersive use	Information requested	Details
[3R-(3α,3aβ,7β,8aα)]-1-(2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-5-yl)ethan-1-one	251-020-3	32388-55-9	2021	Netherlands	Potential endocrine disruptor Suspected PBT/vPvB	Not started	Details
a mixture of: 4-(2,2,3-trimethylcyclopent-3-en-1-yl)-1-methyl-2-oxabicyclo[2.2.2]octane; 1-(2,2,3-trimethylcyclopent-3-en-1-yl)-5-methyl-6-oxabicyclo[3.2.1]octane; spiro[cyclohex-3-en-1-yl-[(4,5,6,6a-tetrahydro-3,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]furan]; spiro[cyclohex-3-en-1-yl-[4,5,6,6a-tetrahydro-4,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]]furan]	422-040-1	426218-78-2	2016	Spain	Suspected PBT/vPvB Exposure of environment High RCR	Information requested	Details
a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol	405-040-6	63500-71-0	2012	Spain	High RCR Wide dispersive use	Concluded	Details
A mixture of: propan-2-one-O,O'(methoxyvinylsilandiyl)dioxime; propan-2-one-O-(dimethoxyvinylsilyl)oxime; propan-2-one-O,O',O''-(vinylsilantriyl)trioxime	458-680-3	797751-44-1	2019	Spain	Suspected PBT/vPvB Exposure of environment	Ongoing	Details
a mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives	421-820-9	192268-65-8	2020	Netherlands	Suspected PBT/vPvB	Not started	Details
Acetic acid, oxo-, sodium salt, reaction products with ethylenediamine and phenol, iron sodium salts	283-044-5	84539-55-9	2020	Sweden	Suspected Reprotoxic Potential endocrine disruptor Suspected Sensitiser Consumer use Exposure of environment Exposure of workers Wide dispersive use	Not started	Details
acetone oxime	204-820-1	127-06-0	2016	Austria	Suspected Carcinogenic Suspected Mutagenic Suspected Sensitiser Exposure of environment Exposure of workers High RCR Wide dispersive use	Concluded	Details
Acrylic acid, monoester with propane-1,2-diol	247-118-0	25584-83-2	2021	France	Suspected Carcinogenic Suspected Mutagenic Suspected Sensitiser Exposure of workers High (aggregated) tonnage High RCR Other exposure/risk based concern Wide dispersive use	Not started	Details
alcohols, C7-9-iso-, C8-rich	271-231-4	68526-83-0	2016	Italy	Suspected Carcinogenic Suspected Mutagenic Consumer use Exposure of workers Wide dispersive use	Concluded	Details
Alkanes, C14-17, chloro (MCCP, Medium chained chlorinated paraffins)	287-477-0	85535-85-9	2012	Sweden	Suspected PBT/vPvB High (aggregated) tonnage Wide dispersive use	Information requested	Details
Aluminium chloride	231-208-1	7446-70-0	2015	France	Suspected CMR Exposure of workers High (aggregated) tonnage High RCR	Information requested	Details
Aluminium chloride basic	215-477-2	1327-41-9	2015	France	Suspected CMR High (aggregated) tonnage	Information requested	Details
Aluminium sulphate	233-135-0	10043-01-3	2015	France	Suspected CMR Suspected Sensitiser Consumer use High (aggregated) tonnage High RCR Wide dispersive use	Information requested	Details
amides, C18-unsatd., N-[3-(dimethylamine)propyl]	800-353-8	1379524-06-7	2016	Germany	Suspected PBT/vPvB Other hazard based concern Exposure of environment High RCR Wide dispersive use	Concluded	Details
Amines, C12-14 (even numbered)-alkyldimethyl, N-oxides	931-292-6	308062-28-4	2020	Ireland	Suspected Reprotoxic Other hazard based concern	Not started	Details
ammonium 2,2,3 trifluor-3-(1,1,2,2,3,3-hexafluoro-3-trifluormethoxypropoxy), propionate	480-310-4	-	2017	Germany	Suspected PBT/vPvB Exposure of environment Wide dispersive use	Ongoing	Details
ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate	700-242-3	62037-80-3	2017	Germany	Suspected PBT/vPvB Exposure of environment	Information requested	Details
ammonium difluoro[1,1,2,2-tetrafluoro-2-(pentafluoroethoxy)ethoxy]acetate	700-323-3	908020-52-0	2017	Germany	Suspected PBT/vPvB Exposure of environment	Ongoing	Details
ammonium perchlorate	232-235-1	7790-98-9	2015	Germany	Suspected Carcinogenic Potential endocrine disruptor Other hazard based concern Exposure of workers High RCR Wide dispersive use	Concluded	Details
Ammonium salts of mono- and bis[3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl and/or poly (substituted alkene)] phosphate	700-403-8	-	2013	Belgium	Suspected PBT/vPvB Consumer use Wide dispersive use	Ongoing	Details
Ammonium thiocyanate	217-175-6	1762-95-4	2015	Czech Republic	Suspected CMR Potential endocrine disruptor High (aggregated) tonnage High RCR Wide dispersive use	Concluded	Details
Amphoteric Fluorinated Surfactant	-	-	2018	Belgium	Suspected PBT/vPvB Exposure of environment Wide dispersive use	Ongoing	Details
Amylase, α-	232-565-6	9000-90-2	2015	United Kingdom	Sensitiser Consumer use Exposure of workers	Concluded	Details
Antimony	231-146-5	7440-36-0	2018	Germany	Suspected Carcinogenic Exposure of workers High (aggregated) tonnage High RCR Other exposure/risk based concern Wide dispersive use	Ongoing	Details
Antimony sulphide	215-713-4	1345-04-6	2018	Germany	Suspected Carcinogenic Exposure of workers High RCR Other exposure/risk based concern Wide dispersive use	Ongoing	Details
Antimony trichloride	233-047-2	10025-91-9	2018	Germany	Suspected Carcinogenic Suspected Reprotoxic	Concluded	Details
Barium bis[2-chloro-5-[(2-hydroxy-1-naphthyl)azo]toluene-4-sulphonate]	225-935-3	5160-02-1	2020	Germany	Suspected Carcinogenic Exposure of workers Wide dispersive use	Not started	Details
Benzaldehyde	202-860-4	100-52-7	2020	France	Suspected Mutagenic Consumer use Exposure of workers Wide dispersive use	Not started	Details
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene	270-128-1	68411-46-1	2016	Germany	Suspected PBT/vPvB Exposure of environment High (aggregated) tonnage Wide dispersive use	Information requested	Details
Benzenamine, reaction products with aniline hydrochloride and nitrobenzene	309-912-6	101357-15-7	2019	Germany	Suspected PBT/vPvB	Ongoing	Details
Benzene, mono-C10-13-alkyl derivs., distn. residues	284-660-7	84961-70-6	2014	Italy	Consumer use High (aggregated) tonnage Suspected PBT/vPvB Wide dispersive use	Information requested	Details
Benzene, mono-C11-C13-branched alkyl derivatives	810-801-4	-	2015	Netherlands	Suspected CMR Suspected PBT/vPvB High (aggregated) tonnage	Ongoing	Details
Benzophenone	204-337-6	119-61-9	2013	Denmark	Suspected CMR Consumer use High RCR Wide dispersive use	Concluded	Details
Benzothiazole-2-thiol	205-736-8	149-30-4	2013	Germany	CMR Sensitiser Consumer use Exposure of sensitive populations High (aggregated) tonnage Wide dispersive use	Concluded	Details
Benzotriazole	202-394-1	95-14-7	2016	Germany	Potential endocrine disruptor Exposure of environment	Information requested	Details
benzyl alcohol	202-859-9	100-51-6	2016	Germany	Suspected Sensitiser Exposure of workers High RCR Wide dispersive use	Follow-up	Details
Benzyl salicylate	204-262-9	118-58-1	2020	Germany	Potential endocrine disruptor	Not started	Details
Beryllium	231-150-7	7440-41-7	2013	Germany	Other exposure/risk based concern	Concluded	Details
Betaines, C12-14 (even numbered)-alkyldimethyl	931-700-2	-	2021	France	Suspected Reprotoxic Other hazard based concern Consumer use Exposure of environment Exposure of workers High (aggregated) tonnage High RCR Wide dispersive use	Not started	Details
Biphenyl	202-163-5	92-52-4	2013	Portugal	Suspected PBT/vPvB High (aggregated) tonnage	Conclusion under preparation	Details
Bis(2,6-diisopropylphenyl)carbodiimide	218-487-5	2162-74-5	2021	Italy	Suspected PBT/vPvB Exposure of environment Wide dispersive use	Not started	Details
bis(2-ethylhexyl) 4,4’-{6-[4-tert-butylcarbamoyl)anilino]-1,3,5-triazine-2,4-diyldiimino}dibenzoate	421-450-8	154702-15-5	2015	Germany	Suspected PBT/vPvB Exposure of environment Wide dispersive use	Information requested	Details
Bis(2-ethylhexyl) adipate	203-090-1	103-23-1	2020	Finland	Suspected CMR Consumer use High (aggregated) tonnage Wide dispersive use	Not started	Details
Bis(2-ethylhexyl) tetrabromophthalate	247-426-5	26040-51-7	2019	Sweden	Potential endocrine disruptor Suspected PBT/vPvB Other hazard based concern Exposure of environment Wide dispersive use	Ongoing	Details
Bis(2-ethylhexyl)amine	203-372-4	106-20-7	2019	Portugal	Suspected PBT/vPvB Exposure of environment	Ongoing	Details
Bis(2-propylheptyl) phthalate	258-469-4	53306-54-0	2020	Germany	Potential endocrine disruptor Exposure of sensitive populations High (aggregated) tonnage Wide dispersive use	Not started	Details
bis(4-chlorophenyl) sulphone	201-247-9	80-07-9	2019	Austria	Suspected PBT/vPvB High (aggregated) tonnage Wide dispersive use	Ongoing	Details
Bis(dibutyldithiocarbamato-S,S')copper	237-695-7	13927-71-4	2020	France	Suspected Reprotoxic Potential endocrine disruptor Suspected PBT/vPvB Exposure of workers	Not started	Details
Bis(isopropyl)naphthalene	254-052-6	38640-62-9	2013	Sweden	Suspected PBT/vPvB High (aggregated) tonnage Wide dispersive use	Information requested	Details
bis(nonafluorobutyl)phosphinic acid	700-183-3	52299-25-9	2018	Germany	Suspected PBT/vPvB Other hazard based concern Exposure of environment	Concluded	Details
Bis(nonylphenyl)amine	253-249-4	36878-20-3	2020	France	Suspected Mutagenic Suspected PBT/vPvB High (aggregated) tonnage	Not started	Details
bis(pentane-2,4-dionato)calcium	243-001-3	19372-44-2	2015	Germany	Sensitiser Other hazard based concern Exposure of workers High (aggregated) tonnage	Ongoing	Details
bis(α,α-dimethylbenzyl) peroxide	201-279-3	80-43-3	2015	Norway	Suspected PBT/vPvB Consumer use Exposure of environment Exposure of workers High (aggregated) tonnage High RCR Wide dispersive use	Information requested	Details
Buta-1,3-diene	203-450-8	106-99-0	2014	Germany	CMR Other exposure/risk based concern	Concluded	Details
Butan-1-ol	200-751-6	71-36-3	2017	Hungary	Suspected Reprotoxic Consumer use Exposure of workers High (aggregated) tonnage Wide dispersive use	Concluded	Details
Butan-2-one O,O',O''-(methylsilylidyne)trioxime	245-366-4	22984-54-9		Italy	Suspected PBT/vPvB Exposure of environment Wide dispersive use	Not started	Details
Butan-2-one O,O',O''-(vinylsilylidyne)trioxime	218-747-8	2224-33-1		Italy	Suspected PBT/vPvB Exposure of environment Wide dispersive use	Not started	Details
Butanone	201-159-0	78-93-3	2018	Sweden	Suspected Reprotoxic Potential endocrine disruptor Consumer use Exposure of environment Exposure of workers High (aggregated) tonnage High RCR Wide dispersive use	Ongoing	Details
Butanone oxime	202-496-6	96-29-7	2013	Germany	CMR Sensitiser Consumer use Cumulative exposure High RCR Wide dispersive use	Concluded	Details
Butyl acrylate	205-480-7	141-32-2	2013	Sweden	Suspected CMR High (aggregated) tonnage Other exposure/risk based concern	Conclusion under preparation	Details
C16-(branched), C20-(branched) and C24-(branched)-alkanes	700-992-1	-	2014	Norway	Suspected PBT/vPvB Consumer use High (aggregated) tonnage Wide dispersive use	Ongoing	Details
Carbon black	215-609-9	1333-86-4	2021	France	Carcinogenic Suspected Reprotoxic Consumer use Cumulative exposure Exposure of sensitive populations Exposure of workers High (aggregated) tonnage Wide dispersive use	Not started	Details
Carbon disulphide	200-843-6	75-15-0	2013	France	CMR Potential endocrine disruptor Exposure of environment Exposure of workers High (aggregated) tonnage	Follow-up	Details
Carbon tetrachloride	200-262-8	56-23-5	2012	France	CMR Exposure of workers High (aggregated) tonnage	Conclusion under preparation	Details
cerium dioxide	215-150-4	1306-38-3	2020	Germany	Suspected Carcinogenic Suspected Mutagenic Other hazard based concern Cumulative exposure Exposure of environment Wide dispersive use	Not started	Details
Chloromethane	200-817-4	74-87-3	2012	Italy	CMR Potential endocrine disruptor High RCR	Concluded	Details
Chromium (III) oxide	215-160-9	1308-38-9	2019	France	Suspected Reprotoxic Suspected Sensitiser High (aggregated) tonnage	Ongoing	Details
Citral	226-394-6	5392-40-5	2015	Sweden	Sensitiser Consumer use Exposure of workers High (aggregated) tonnage Wide dispersive use	Concluded	Details
Citronellal	203-376-6	106-23-0	2015	Sweden	Sensitiser Consumer use Exposure of workers High (aggregated) tonnage Wide dispersive use	Concluded	Details
Climbazole	253-775-4	38083-17-9	2014	Belgium	Suspected CMR Consumer use Wide dispersive use	Information requested	Details
Cyclohexanone	203-631-1	108-94-1	2016	Poland	Suspected Carcinogenic Suspected Mutagenic Suspected Reprotoxic Exposure of workers High (aggregated) tonnage Wide dispersive use	Concluded	Details
Cyclohexylamine	203-629-0	108-91-8	2016	Belgium	Reprotoxic Exposure of environment High (aggregated) tonnage	Concluded	Details
Dapsone	201-248-4	80-08-0	2016	Germany	Potential endocrine disruptor	Concluded	Details
decahydronaphthalene	202-046-9	91-17-8	2012	Finland	Suspected PBT/vPvB High (aggregated) tonnage	Follow-up	Details
decamethyltetrasiloxane	205-491-7	141-62-8	2015	Norway	Suspected PBT/vPvB Exposure of environment Wide dispersive use	Follow-up	Details
Decan-1-ol	203-956-9	112-30-1	2012	Italy	Other hazard based concern High (aggregated) tonnage Other exposure/risk based concern Wide dispersive use	Concluded	Details
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	229-782-3	6731-36-8	2014	Germany	Suspected PBT/vPvB	Follow-up	Details
Di-tert-butyl peroxide	203-733-6	110-05-4	2016	Netherlands	CMR Consumer use High (aggregated) tonnage Wide dispersive use	Ongoing	Details
di-tert-pentyl peroxide	234-042-8	10508-09-5	2015	Italy	Suspected Carcinogenic Suspected Mutagenic Exposure of workers Wide dispersive use	Follow-up	Details
Diallyl phthalate	205-016-3	131-17-9	2013	Spain	CMR Consumer use Wide dispersive use	Concluded	Details
Diantimony trioxide	215-175-0	1309-64-4	2018	Germany	Carcinogenic Exposure of workers High (aggregated) tonnage High RCR Other exposure/risk based concern Wide dispersive use	Ongoing	Details
Dichloro(dimethyl)silane	200-901-0	75-78-5	2014	Czech Republic	Suspected PBT/vPvB High (aggregated) tonnage	Concluded	Details
Dichloromethane	200-838-9	75-09-2	2016	Italy	Carcinogenic Suspected Mutagenic Suspected Reprotoxic Potential endocrine disruptor Suspected Sensitiser High (aggregated) tonnage	Ongoing	Details
Dicyclohexyl phthalate DCHP	201-545-9	84-61-7	2017	Sweden	Potential endocrine disruptor Exposure of environment Wide dispersive use	Information requested	Details
Diethyl ether	200-467-2	60-29-7	2020	France	Suspected Carcinogenic Suspected Mutagenic Suspected Reprotoxic Other hazard based concern Consumer use Exposure of environment High (aggregated) tonnage Wide dispersive use	Not started	Details
diethyl phthalate	201-550-6	84-66-2	2014	Germany	CMR Potential endocrine disruptor Consumer use High (aggregated) tonnage Wide dispersive use	Concluded	Details

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Last updated 13 December 2019. Database contains 375 unique substances/entries.

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