Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
EM/00460 DSC - Schmelztemperatur (DIN EN ISO 11357-3)
GLP compliance:
no
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
140.9 °C
Atm. press.:
1 013 hPa

Any other information on results incl. tables

 Result

Sample

Tm1

[°C]

Tk*

[°C]

∆m

[%]

1H-Pyrazole-4-carboxylic acid, 1-(1,2- dimethylpropyl)-5-methyl-

140.9

-

15

Explanations

Tm1= melting peak temperature in delivery condition

Tk* = crystallisation temperature

∆m = weight loss, determined at the end of the measurement

Due to the wide intake, an evaluation of the onset temperature does not make sense. In the cooling run, no crystallization is detectable.
In a first measurement up to 160 ° C showed a strong thermal degradation of the sample with a weight loss of about 31%, so that a maximum temperature was chosen just above the melting peak for the present measurement

Applicant's summary and conclusion