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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 23rd of July 1998 to 28th of July 1998.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999
Report date:
1999

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: EEc method No. A.6
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
444-810-6
EC Name:
-
Molecular formula:
C27 H30 N2 * C10 H16 O4 S
IUPAC Name:
(2S-cis)-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2.]octan-3-amine (1-R camphor-10-sulfonate)
Test material form:
solid: particulate/powder

Results and discussion

Water solubility
Key result
Water solubility:
ca. 4.43 g/L
Loading of aqueous phase:
500 other: mg in 25 ml purified water
Temp.:
20 °C
pH:
>= 6.15 - <= 6.43
Details on results:
No peaks were observed in the chromatograms of the blank solutions indicating that the analytical
method was free from interference.

Applicant's summary and conclusion

Conclusions:
The water solubility of CP-163,625-BV was found to be 4.43 g/l.
Executive summary:

The water solubility of CP-163,625-BV was found to be 4.43 g/l.