Registration Dossier
Registration Dossier
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EC number: 821-749-7 | CAS number: 154581-97-2
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Short-term aquatic toxicity data are available for three trophic levels (Algae, Daphnia and fish). The E(L)C50s are > 0.065, 0.247 and 1.7 mg/L, respectively. The lowest acute toxicity data is for Daphnia with an EC50 value of 0.247 mg/l (<1.0 mg/)L. Based on this data the substance needs to be classified for acute aquatic hazard, Category Acute 1, H400: Very toxic to aquatic life (CLP 2008, and its amendments: Table 4.1.0 (a)).
Long-term toxicity is available for alga and Daphnia. The NOEC for algae is NOEC >= 0.065 mg/L and the EC10 for Daphnia is 0.069 mg/l. The latter value of Daphnia is used because it is a point value. Therefore, both chronic toxicity data (in combination with biodegradability) and acute toxicity data (in combination with biodegradability and/or Log Kow) need to be assessed and the most stringent outcome needs to be applied for long-term aquatic hazard classification (CLP 2008, and its amendments: Figure 4.1.1.).
Based on the EC10 for Daphnia being 0.069 mg/L, the substance needs to be classified for long-term aquatic hazard according to Table 4.1.0(b)ii, resulting in Category Chronic 2. This classification is similar when it would have been based on the the acute toxicity data on fish, which is the other trophic level because algae do not have a point value. Based on acute fish toxicity: LC50 of 1.7 mg/L and the Log Kow of 5.2 (despite being readily biodegradable), the substance needs to be classified as Category Chronic 2 according to Table 4.1.0(b)iii.
Overall: Based on acute data the substance needs to be classified for acute aquatic hazard, Category Acute 1, H400: Very toxic to aquatic life (CLP 2008, and its amendments: Table 4.1.0 (a)). For long-term aquatic hazard the substance needs to be classified as Category Chronic 2, H411: Toxic to aquatic life with long lasting effects, according to Regulation 1272/2008/EC (CLP) and its amendments.
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