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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Type of method:
flask method
Key result
Water solubility:
774 g/L
Temp.:
20 °C
pH:
10.4
Conclusions:
The test item HEDP #13082 Nachsubstanz has a water solubility of 774 g/L at 20°C.
Endpoint:
water solubility
Type of information:
other: Data from MSDS
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Principles of method if other than guideline:
No information
Type of method:
other: None reported
Remarks on result:
completely miscible
Remarks:
The substance was reported as miscible in water
Conclusions:
The substance was reported as miscible in water in a MSDS
Endpoint:
water solubility
Type of information:
other: Data from MSDS
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Principles of method if other than guideline:
No information
Type of method:
other: None reported
Water solubility:
>= 530 g/L
Temp.:
20 °C
pH:
ca. 7 - ca. 8.5
Remarks on result:
completely miscible
Remarks:
The substance was reported as fully miscible in water. Based on concentration of 39-43% at 20°C and since the solution density is much higher than 1, the equivalent water solubility in g/L using density and concentration is reported as ≥530 g/L.
Conclusions:
The substance was reported as fully miscible in water in a MSDS
Endpoint:
water solubility
Type of information:
other: Data from MSDS
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Principles of method if other than guideline:
No information
Type of method:
other: None reported
Water solubility:
ca. 230 - ca. 280 g/L
Temp.:
20 °C
pH:
ca. 5.8 - ca. 6.5
Remarks on result:
completely miscible
Remarks:
The substance was reported as fully miscible in water. Based on concentration of 20-24% at 20°C and since the solution density is much higher than 1, the equivalent water solubility in g/L using density and concentration is reported as ≥230 g/L.
Conclusions:
The substance was reported as fully miscible in water in a MSDS

Description of key information

Water solubility: Commercially available HEDP-xK in the form of aqueous solution products at typically 20% w/w to 43% w/w are miscible in water.

Key value for chemical safety assessment

Water solubility:
230 g/L
at the temperature of:
20 °C

Additional information

In support of the Key data, it is notable that in general, phosphonate salts are highly hydrophilic and extremely water soluble. Free acids are less soluble than the salts; however, aqueous solutions in excess of 1% active acid material can be prepared.

In available secondary sources, HEDP-xK was reported as miscible or freely miscible in water with reported concentrations of 20 - 43% at 20°C but it is not clear from the source report whether this is expressed as %w/w, %v/v or %w/v. Since the solution density is much higher than 1, the equivalent water solubility in g/L using density and concentration is reported as ≥230 g/L. In addition, as the value is known to be extremely high, the exact value is considered not significant for the chemical safety assessment for human health or environmental assessment and this limit value is therefore sufficient and is considered to be reliable. In addition, a measured water solubility of 774 g/L at 20°C is determined for the tetrasodium salt of HEDP (HEDP-4Na) using a relevant test method. The available data are used as weight of evidence to indicate that the substance is highly soluble in water.