Registration Dossier

Administrative data

Description of key information

This substance is not a skin irritant, is an eye irritant at 100%, but not an eye irritant at a 50 percent concentration.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

No data on respiratory irritation are available for the test material.

No skin irritation was observed in an animal study in which the test substance was administered as supplied and held in place under semi-occlusive wrap for 4 hours.

At 100%, the test material hadirritant effects on the mucous membranes of the eyes, not reversible within 21 days in three of six rabbits, butat 50 percent concentration, no ocular irritation was observed. The studies are found to be adequate to fulfill the purposes of this endpoint.

The following information is taken into account for any hazard / risk assessment:

This substance is not a skin irritant, is an eye irritant at 100%, but not an eye irritant at a 50 percent concentration.


Effects on eye irritation: irritating

Justification for classification or non-classification

There are conclusive but not sufficient data for classification of the test material with regard to skin irritation / corrosion, so the test material is not classified for this endpoints in accordance to Directive 67/548/EEC or the CLP Regulation (EC) No 1272/2008.

 

The test material is classified for eye irritation endpoints in accordance to Directive 67/548/EEC or the CLP Regulation (EC) No 1272/2008.