These documents provide practical information on requirements under REACH, CLP and BPR, and best practice on how to fulfil them.
Where relevant, find the translated versions of the practical guides by selecting your language from the drop-down menu at the top right of the screen.
- How to prepare and develop a Substance Identity Profile (SIP) [PDF] [EN]
- How to act in substance evaluation [PDF] [EN]
25 July 2019 - Disclaimer: the text in Section 6.4 (page 26-27), is currently under revision and will be updated as soon as possible.
- Practical guide for SME managers and REACH coordinators - How to fulfil your information requirements at tonnages 1-10 and 10-100 tonnes per year [PDF] [EN]
- How to use alternatives to animal testing to fulfil your information requirements for REACH registration [PDF] [EN]
- How to use and report (Q)SARs [PDF] [EN]
- How to report robust study summaries[PDF]
- How to report changes in identity under REACH and CLP [PDF] [EN]
- How to act in dossier evaluation [PDF]
- How downstream users can handle exposure scenarios [PDF]
- How to prepare toxicological summaries in IUCLID and how to derive DNELs [PDF]
- How to undertake a qualitative human health assessment and document it in a chemical safety report [PDF] [EN]
- How to assess whether a substance is used as an intermediate under strictly controlled conditions and how to report the information for the intermediate registration in IUCLID [PDF]
- How to prepare a downstream user chemical safety report [PDF]
ECHA has withdrawn the following practical guides, as their content has been integrated in the Practical guide on how to use alternatives to animal testing to fulfil your information requirements under REACH:
- Practical Guide 1: How to report in vitro data
- Practical Guide 2: How to report weight of evidence
- Practical Guide 4: How to report data waiving
- Practical Guide 6: How to report read-across and categories
- Practical Guide 10: How to avoid unnecessary testing on animals